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Triple combination asthma inhaler works in patients with persistent airflow limitation
A novel once-a-day inhaler for asthma that contains a fixed-dose combination of the corticosteroid mometasone furoate (MF), the long-acting beta-agonist indacaterol acetate (IND), and the long-acting muscarinic antagonist glycopyrronium bromide (GLY) appears to have a favourable effect in patients with persistent airflow limitation (PAL), according to a post hoc analysis of the IRIDIUM study.
Triple combination asthma inhaler works in patients with persistent airflow limitation
17 Mar 2023Dietary phosphorus intake tied to diabetes risk
Too much and too little consumption of phosphorus in the diet are deemed risky in relation to the likelihood of developing diabetes, with a study showing a U-shaped association between the phosphorous intake and new-onset diabetes.
Dietary phosphorus intake tied to diabetes risk
17 Mar 2023Novel meningitis/encephalitis CSF testing shortens antiviral prescribing duration
The duration of antiviral prescribing has become much shorter with the introduction of the Biofire Filmarray meningitis/encephalitis (M/E) panel, a study has shown. However, its influence on antibiotic prescribing or health services in a paediatric hospital is minimal.
Novel meningitis/encephalitis CSF testing shortens antiviral prescribing duration
16 Mar 2023Weight loss in early adulthood delays biological ageing
Weight gain among adults appears to speed up a person’s biological age, with a recent study showing the associations of maximal overweight, nonobese to obese, and stable obesity across adulthood with accelerated biological ageing. On the other hand, weight loss from young to middle adulthood tends to slow down biological ageing.
Weight loss in early adulthood delays biological ageing
16 Mar 2023C3 levels tied to incident T2DM; BMI plays a mediating role
Complement C3 levels may be used as a predictor of incident type 2 diabetes mellitus (T2DM), suggests a study. In addition, body mass index (BMI) may have a mediating role in the association between C3 and T2DM, offering clues for diabetes pathogenesis.
C3 levels tied to incident T2DM; BMI plays a mediating role
16 Mar 2023Cyclophosphamide-free adjuvant chemo works against ERBB2-negative breast cancer
The adjuvant chemotherapy regimen epirubicin plus paclitaxel (EP) appears to be as good as the regimen that consists of epirubicin and cyclophosphamide followed by paclitaxel (EC-P) in the treatment of Asian women with operable ERBB2-negative breast cancer, according to the results of an open-label phase III trial.
Cyclophosphamide-free adjuvant chemo works against ERBB2-negative breast cancer
15 Mar 2023Pituitary-targeting seliciclib shows promise in treatment of Cushing disease
In a recent study, seliciclib therapy demonstrates its potential in reversing hypercortisolism by directly targeting pituitary corticotrophs in Cushing disease (CD). However, the agent is associated with liver toxicity, which is resolved by withdrawing treatment.