News &amp; Updates

Adjunctive prazosin helps battle nightmares in PTSD

Use of prazosin in the adjunctive setting shows some utility in reducing the frequency of nightmares in patients with post-traumatic stress disorder (PTSD) who are already receiving first-line treatment, according to a study.

Adjunctive prazosin helps battle nightmares in PTSD

Cyproheptadine shows therapeutic potential in individuals with poor appetite

Cyproheptadine appears to be a safe and effective appetite stimulant in adults with poor appetite, according to a study from South Korea.

Cyproheptadine shows therapeutic potential in individuals with poor appetite

Drinking sufficient water may help prevent HF

11 Sep 2021 by

Having high serum sodium levels above 142 mmol/L — which is indicative of insufficient fluid intake — is associated with a greater risk of left ventricular hypertrophy (LVH) and heart failure (HF) in later life, according to the ARIC* study presented at ESC 2021 Congress.

Drinking sufficient water may help prevent HF

Poststroke fluoxetine exerts null effect on functional outcome

Use of fluoxetine following stroke confers no benefit for functional outcome after 1 year and may potentially affect memory and communication, according to a secondary analysis of the EFFECTS study.

Poststroke fluoxetine exerts null effect on functional outcome

Markers of proliferation, apoptosis in breast cancer similar between vandetanib, placebo

A pilot study of preoperative vandetanib has found no statistically significant differences on prespecified markers when compared with placebo.

Markers of proliferation, apoptosis in breast cancer similar between vandetanib, placebo

Prolonged dydrogesterone exposure helps relieve chronic pelvic pain, dysmenorrhoea

Prolonged cyclical and continuous treatment regimens of dydrogesterone produce similar reduction in the severity of chronic pelvic pain and dysmenorrhoea, resulting in marked improvements in quality of life and sexual wellbeing, according to a study.

Prolonged dydrogesterone exposure helps relieve chronic pelvic pain, dysmenorrhoea

Cemiplimab extends OS in recurrent/metastatic cervical cancer

10 Sep 2021 by

Cemiplimab appears to extend overall survival (OS) compared with investigator’s choice (IC) of chemotherapy in patients with recurrent or metastatic (R/M) cervical cancer who have progressed on first-line platinum-based chemotherapy, results of the phase III EMPOWER-Cervical 1/GOG-3016/ENGOT-cx9 trial showed.

Cemiplimab extends OS in recurrent/metastatic cervical cancer

Ketoprofen as good as diclofenac plasters for relieving aching knee

10 Sep 2021 by

Topical ketoprofen and diclofenac yield comparable analgesic effects in the treatment of pain in patients with knee osteoarthritis, with ketoprofen having a favourable safety profile, as shown in a phase III study.

Ketoprofen as good as diclofenac plasters for relieving aching knee

PPIs safe to use with capecitabine-based NACRT for locally advanced rectal cancer

Concomitant use of proton pump inhibitors (PPIs) with capecitabine-based neoadjuvant chemoradiotherapy (NACRT) for locally advanced rectal cancer (LARC) is safe and does not result in any adverse pathologic or oncological outcome, reports a study.

PPIs safe to use with capecitabine-based NACRT for locally advanced rectal cancer