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Diet with hyperinsulinaemic potential ups risk of breast cancer
Women with a dietary pattern contributing to hyperinsulinaemia and insulin resistance appear to be at increased risk of breast cancer, particularly estrogen-receptor (ER)-negative and human epidermal growth factor receptor 2 (HER2)-enriched tumours, reveals a study.
Diet with hyperinsulinaemic potential ups risk of breast cancer
15 Jan 2023PFS in relapsed/refractory CLL/SLL: Zanubrutinib triumphs over ibrutinib
The second-generation BTK* inhibitor zanubrutinib was superior to the standard-of-care ibrutinib in improving progression-free survival (PFS) among patients with relapsed/refractory chronic lymphocytic leukaemia (R/R CLL) or small lymphocytic lymphoma (SLL), according to results of the phase III ALPINE trial presented at ASH 2022.
PFS in relapsed/refractory CLL/SLL: Zanubrutinib triumphs over ibrutinib
15 Jan 2023Etanercept biosimilar demonstrates long-term safety, efficacy in rheumatoid arthritis
YLB113, a biosimilar of the reference product etanercept, appears to be safe for long-term treatment of patients with rheumatoid arthritis, with efficacy sustained for up to 96 weeks, according to a study. Notably, the biosimilar is associated with fewer cases of injection-site reactions and injection-site erythema compared with the reference.