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Dual inhibition of LAG-3, PD-1: a new therapeutic target for advanced melanoma?
In the phase II/III RELATIVITY-047 trial evaluating dual checkpoint inhibition for advanced melanoma, a new fixed-dose combination comprising the LAG-3 inhibitor relatlimab and the PD-1 inhibitor nivolumab fared better than nivolumab monotherapy.
Dual inhibition of LAG-3, PD-1: a new therapeutic target for advanced melanoma?
25 Feb 2022
AI as good as experts at detecting melanomas
Convolutional neural networks (CNN) can outperform less-experienced pathologists at discriminating melanomas from nevi, reports a recent study. For experienced pathologists, CNNs may still be helpful as a form of triage.
AI as good as experts at detecting melanomas
23 Feb 2022
Microneedle technology on par with topical steroids in nail psoriasis treatment
A novel transdermal device for the delivery of triamcinolone demonstrates efficacy comparable to that of conventional topical steroids in the treatment of nail psoriasis, according to a Singapore study.
Microneedle technology on par with topical steroids in nail psoriasis treatment
15 Feb 2022
Reaction patterns may aid in diagnosis of COVID-19 vaccine-related cutaneous side effects
A registry-based study has recently shown diverse COVID-19 vaccine-associated dermatologic reactions, including papulovesicular, pityriasis rosea-like, and papulosquamous eruptions classified as vaccine-related eruption of papules and plaques (V-REPP).
Reaction patterns may aid in diagnosis of COVID-19 vaccine-related cutaneous side effects
02 Feb 2022
Secukinumab safe, effective in children with moderate to severe plaque psoriasis
Treatment with either low- or high-dose secukinumab is effective and well tolerated in paediatric patients with moderate to severe plaque psoriasis, a study has shown.
Secukinumab safe, effective in children with moderate to severe plaque psoriasis
31 Jan 2022
Depression rife in hidradenitis suppurativa
The prevalence of depression is relatively high among children, adolescents, and adults with hidradenitis suppurativa (HS), a chronic inflammatory skin disorder, according to a study, which also notes the importance of periodic screening for depression.