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Obesity, overweight up risk of complications from radical cystectomy
Body mass index is independently associated with the development of complications from radical cystectomy, reports a study. Compared to patients with normal BMI, those who are overweight and obese have a higher risk.
Obesity, overweight up risk of complications from radical cystectomy
20 Dec 2022EMERALD updates highlight therapeutic potential of elacestrant for ER+/HER2– mBC
In the updated analysis of the phase III EMERALD trial, the next-generation oral SERD* elacestrant continued to show favourable signals for the treatment of ER+/HER2– metastatic breast cancer (mBC).
EMERALD updates highlight therapeutic potential of elacestrant for ER+/HER2– mBC
20 Dec 2022Metformin may reduce COVID-19 severity in prediabetes, PCOS
Among patients with prediabetes or polycystic ovary syndrome (PCOS), the use of metformin appears to be associated with lower incidence of severe COVID-19, according to a study.
Metformin may reduce COVID-19 severity in prediabetes, PCOS
19 Dec 2022Bepirovirsen shows promise in controlling chronic HBV infection
Weekly bepirovirsen treatment may help reduce HBsAg* and hepatitis B virus (HBV) DNA levels in patients with chronic HBV infection, the phase IIb B-Clear study showed.
Bepirovirsen shows promise in controlling chronic HBV infection
19 Dec 2022Can vitamin D ease overactive bladder, urinary incontinence symptoms in older men?
Supplementation with vitamin D does not lead to improvements in overactive bladder or urinary incontinence relative to placebo, a study has shown. However, specific use of vitamin D in men with lower 25-hydroxyvitamin D levels shows inconsistent results.
Can vitamin D ease overactive bladder, urinary incontinence symptoms in older men?
19 Dec 2022Maintenance olaparib confers survival benefit for HRD+ ovarian cancer patients
In the final overall survival (OS) analysis of the phase III PAOLA-1*/ENGOT-ov25 trial, the addition of olaparib to bevacizumab provided a survival benefit for women with newly diagnosed advanced ovarian cancer with HRD**-positive (HRD+) tumours.
Maintenance olaparib confers survival benefit for HRD+ ovarian cancer patients
19 Dec 2022Gestational diabetes mellitus predisposes women to prediabetes, T2DM
Among women with a history of gestational diabetes mellitus (GDM), the conversion to prediabetes or type 2 diabetes mellitus (T2DM) appears to be high, a recent study has found.