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Dolutegravir: A better choice for HIV viral suppression in pregnancy?
Among pregnant individuals on antiretroviral therapy (ART) for HIV-1 infection, those on dolutegravir had the greatest viral suppression rates at delivery, a recent US-based observational study showed. However, birth outcomes generally did not differ between dolutegravir recipients and those on various other ART regimens.
Dolutegravir: A better choice for HIV viral suppression in pregnancy?
13 Nov 2022Polygenic risk scores predict response to ECT for major depressive disorder
A polygenic liability for major depressive disorder and bipolar disorder contributes to improvements following electroconvulsive therapy (ECT), reports a study. This provides evidence of a genetic factor for clinical response to ECT.
Polygenic risk scores predict response to ECT for major depressive disorder
13 Nov 2022Once-weekly semaglutide safe, effective in type 2 diabetes patients
Initiating a once-weekly treatment regimen of semaglutide helps control glycated haemoglobin (HbA1c) levels and body weight in patients with type 2 diabetes, without introducing new safety concerns, a Japan study has found.
Once-weekly semaglutide safe, effective in type 2 diabetes patients
13 Nov 2022Genetic, environmental factors drive metabolic disorder-related depression
The risk of depression is higher in individuals with endocrine-metabolic disorders, which can be explained by genetic and environmental influences, reveals a study.
Genetic, environmental factors drive metabolic disorder-related depression
12 Nov 2022Cinnamic aldehyde, alcohol cause reactions in fragrance allergy
A prospective study has revealed that cinnamic aldehyde and cinnamic alcohol are the most common allergens that cause immediate and delayed reactions among patients with allergic contact dermatitis to fragrance. In addition, reactions to benzyl alcohol, sorbic acid, and coumarin are usually seen in immediate patch tests.
Cinnamic aldehyde, alcohol cause reactions in fragrance allergy
12 Nov 2022Toe amputation effective in diabetics
Transmetatarsal amputation (TMA) appears to be an effective approach in diabetes management and can help avoid lower-extremity amputations (LEA), a recent study has found. However, patient-related factors such as insulin dependence and serum albumin affect the procedure’s efficacy.
Toe amputation effective in diabetics
12 Nov 2022Upper-airway microbes predict asthma exacerbations despite inhaler treatment
Asthma exacerbations after treatment with inhaled corticosteroids (ICS) might be affected by upper-airway microbiome composition and diversity, a new study has found.