News & Updates

Metoprolol good for preventing AF following cardiac surgery

16 Dec 2020 by

Prophylactic use of the beta blocker metoprolol in patients undergoing open heart surgery is effective, leading to a lower incidence of postoperative atrial fibrillation (POAF) compared with placebo, according to a systematic review and meta-analysis.

Metoprolol good for preventing AF following cardiac surgery

16 Dec 2020

VTE prophylaxis does not reduce bleeding, mortality in medically ill patients

16 Dec 2020

Routine administration of venous thromboembolism (VTE) prophylaxis to medically ill patients at high risk for thrombosis significantly increases the risk of bleeding and has no clear clinical benefit, reveals a recent study, noting that the current practice must be reassessed.

VTE prophylaxis does not reduce bleeding, mortality in medically ill patients

16 Dec 2020

BMI does not affect outcomes with dabigatran-based dual therapy

16 Dec 2020 by

In comparison with warfarin-based triple therapy (warfarin TT), the reduction in bleeding rates with dabigatran-based dual therapy (dabigatran DT) appears consistent across body mass index (BMI) categories in patients with atrial fibrillation (AF) after PCI*, according to a subanalysis of the RE-DUAL PCI** trial.

BMI does not affect outcomes with dabigatran-based dual therapy

16 Dec 2020

AFFIRM-AHF: IV iron cuts risk of HF readmissions

15 Dec 2020 by

Intravenous (IV) iron supplementation with ferric carboxymaltose (FCM) reduces the risk of subsequent hospitalization for heart failure (HF) in iron-deficient patients after an episode of acute HF, shows the AFFIRM-AHF trial presented at the AHA 2020 Meeting.

AFFIRM-AHF: IV iron cuts risk of HF readmissions

15 Dec 2020

Statins come to e of patients with acute large vessel occlusion

15 Dec 2020 by

Initiating statin therapy immediately after onset of large vessel occlusion in acute ischaemic stroke patients proves beneficial, leading to better functional outcome and lower mortality at 90 days, according to data from the RESCUE*‐Japan Registry 2.

Statins come to e of patients with acute large vessel occlusion

15 Dec 2020

Off-label morphine sulfate ups risks of death, overdose in OUD patients

15 Dec 2020

Initiation of off-label morphine sulfate (MS) for nonchronic pain in patients with opioid use disorder (OUD) instead of conventional opioid substation treatments (OSTs) is associated with higher overdose, death, bacterial infection, abuse, and diversion risks, according to a study.

Off-label morphine sulfate ups risks of death, overdose in OUD patients

15 Dec 2020

Original New Drug Application Approvals by US FDA (01 - 15 December 2020)

15 Dec 2020

New drug applications approved by US FDA as of 01 - 15 December 2020 which includes New Molecular Entities (NMEs) and new biologics. It does not include Tentative Approvals. Supplemental approvals may have occurred since the original approval date.

Original New Drug Application Approvals by US FDA (01 - 15 December 2020)

15 Dec 2020

Niraparib improves PFS in Chinese patients with ovarian cancer

15 Dec 2020 by

An individualized dosing regimen of niraparib, a potent inhibitor of PARP 1/2, resulted in significantly improved progression-free survival (PFS) among Chinese patients with platinum-sensitive recurrent (PSR) ovarian cancer, according to a subgroup analysis of the NORA* study presented at ESMO Asia 2020.

Niraparib improves PFS in Chinese patients with ovarian cancer

15 Dec 2020

Can common BP-lowering drugs keep breast cancer in check?

14 Dec 2020 by

Angiotensin receptor blockers, used to treat high blood pressure (BP), appear to confer dose-dependent survival benefits on breast cancer patients when taken either prior to or after diagnosis, a study has found.

Can common BP-lowering drugs keep breast cancer in check?

14 Dec 2020

NOACs lower renal function decline in AF patients

14 Dec 2020

A prescription of nonvitamin K antagonist (VKA) oral anticoagulants (NOACs) in patients with atrial fibrillation (AF) leads to a lower renal function worsening compared to those receiving VKAs, suggests a recent study, adding that such effect is partially lost in diabetic patients.

NOACs lower renal function decline in AF patients

14 Dec 2020

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Metoprolol good for preventing AF following cardiac surgery

Metoprolol good for preventing AF following cardiac surgery

VTE prophylaxis does not reduce bleeding, mortality in medically ill patients

VTE prophylaxis does not reduce bleeding, mortality in medically ill patients

BMI does not affect outcomes with dabigatran-based dual therapy

BMI does not affect outcomes with dabigatran-based dual therapy

AFFIRM-AHF: IV iron cuts risk of HF readmissions

AFFIRM-AHF: IV iron cuts risk of HF readmissions

Statins come to e of patients with acute large vessel occlusion

Statins come to e of patients with acute large vessel occlusion

Off-label morphine sulfate ups risks of death, overdose in OUD patients

Off-label morphine sulfate ups risks of death, overdose in OUD patients

Original New Drug Application Approvals by US FDA (01 - 15 December 2020)

Original New Drug Application Approvals by US FDA (01 - 15 December 2020)

Niraparib improves PFS in Chinese patients with ovarian cancer

Niraparib improves PFS in Chinese patients with ovarian cancer

Can common BP-lowering drugs keep breast cancer in check?

Can common BP-lowering drugs keep breast cancer in check?

NOACs lower renal function decline in AF patients

NOACs lower renal function decline in AF patients