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Trial of two tenofovir-containing regimens for HIV/HBV co-infection: Insights from ALLIANCE
The triplet combination of bictegravir/emtricitabine/tenofovir alafenamide (B/F/TAF) is as good as dolutegravir + emtricitabine/tenofovir disoproxil fumarate (DTG+F/TDF) in terms of efficacy for HIV control but results in better hepatitis B virus (HBV) outcomes in patients with HIV/HBV co-infection, according to results of the phase III ALLIANCE trial presented at IAS 2022.
Trial of two tenofovir-containing regimens for HIV/HBV co-infection: Insights from ALLIANCE
24 Aug 2022Measuring patient-based changes in temperature could improve COVID-19 detection in nursing homes
Among nursing home residents, rather than using a one-size-fits-all threshold temperature, looking at individual changes in body temperature and temperature variability, could lead to better prediction of COVID-19 infection, a recent study has found.
Measuring patient-based changes in temperature could improve COVID-19 detection in nursing homes
24 Aug 2022Infusion-to-injection infliximab switch safe, helps lower risk of IBD relapse for some patients
Switching from intravenous to subcutaneous infliximab appears to be safe and well-accepted, resulting in a reduced risk of relapse in some inflammatory bowel disease (IBD) patients, according to data from the REMSWITCH study.
Infusion-to-injection infliximab switch safe, helps lower risk of IBD relapse for some patients
24 Aug 2022Relapse prevention interventions effective in MDD
In patients with remitted major depressive disorder (MDD), the use of psychological relapse prevention interventions, whether as a standalone or in combination with medication, effectively reduces the risk of relapse/recurrence, according to a recent meta-analysis.
Relapse prevention interventions effective in MDD
24 Aug 2022Cholesterol, creatinine, platelet count tied to myocardial infarction, angina pectoris
Among the biochemical indices of obesity, cholesterol, creatinine, and platelet count appear to correlate with myocardial infarction or angina pectoris in both men and women, reports a recent study. Other indicators, including anthropometric measures, varied between sexes.
Cholesterol, creatinine, platelet count tied to myocardial infarction, angina pectoris
23 Aug 2022OASIS-1: Thumbs up for mirikizumab in moderate-to-severe plaque psoriasis
The interleukin (IL)-23 inhibitor mirikizumab demonstrates superior efficacy in the treatment of patients with moderate-to-severe plaque psoriasis as compared with placebo, with initial responses during induction preserved through the maintenance phase, according to the results of the phase III OASIS-1 trial.
OASIS-1: Thumbs up for mirikizumab in moderate-to-severe plaque psoriasis
23 Aug 2022FLT3 inhibitor improves survival in patients with FLT3+ acute myeloid leukaemia
Patients diagnosed with acute myeloid leukaemia with an FLT3 mutation (FLT3+ AML) may benefit from the addition of an FLT3 inhibitor to intensive chemotherapy postinduction by improving event-free (EFS) or overall survival (OS), suggests a study.