News &amp; Updates

Topical OCS-01, a dexamethasone ophthalmic suspension, appears to be beneficial in the treatment of patients with diabetic macular edema, with the results of a phase II study showing that the drug helps improve central macular thickness.

Dexamethasone eye drops show therapeutic potential in diabetic macular edema

$Diabetes ups risk of nonvertebral fractures in postmenopausal women with obesity$

Diabetes ups risk of nonvertebral fractures in postmenopausal women with obesity

Postmenopausal women with obesity are at heightened risk of developing nonvertebral fractures in the presence of type 2 diabetes mellitus (T2DM), a study has found.

Diabetes ups risk of nonvertebral fractures in postmenopausal women with obesity

Patients prefer being awake but sedated during urologic procedures

04 Aug 2022 by

Patients prefer conscious sedation over general anaesthesia (GA) during urologic procedures, according to Canadian researchers who followed patients undergoing various endourologic, ureteric, urethral, or advanced cystoscopic procedures.

Patients prefer being awake but sedated during urologic procedures

Treatment regimen based on small RNAi safe, effective in chronic hepatitis B

In patients with chronic hepatitis B (CHB), treatment with the small interfering RNA JNJ-3989, in combination with a nucleos(t)ide analogue (NA), safely reduces levels of the hepatitis B surface antigen (HBsAg) for up to almost a year after the last dose, a new study has found.

Treatment regimen based on small RNAi safe, effective in chronic hepatitis B

03 Aug 2022

FLASH: Light-activated hypericin ointment gets high marks in early-stage mycosis fungoides

Photodynamic therapy using topically applied hypericin 0.25% is effective against early-stage patch and plaque lesions in patients with mycosis fungoides−cutaneous T-cell lymphoma, while having a favourable safety profile, as shown in the phase III FLASH trial.

FLASH: Light-activated hypericin ointment gets high marks in early-stage mycosis fungoides

Bone surgery at lower-volume hospitals does not compromise survival, readmission

Surgical treatment for metastatic disease of bone (MDB) at lower-volume hospitals is not associated with poorer survival or more readmissions, according to a study.

Bone surgery at lower-volume hospitals does not compromise survival, readmission

Do cardiovascular drugs worsen COVID-19 outcomes?

Cardiovascular medications, such as angiotensin-converting enzyme inhibitors (ACEIs)/angiotensin receptor blocker (ARBs) and anticoagulants, do not induce poor clinical outcomes in patients with COVID-19 and thus should not be discontinued, suggest the results of a meta-analysis.

Do cardiovascular drugs worsen COVID-19 outcomes?

03 Aug 2022

GLP-1 RAs help lower serum uric acid concentration

Treatment with glucagon-like peptide-1 receptor agonists (GLP-1 RAs), a drug class mainly used for the management of type 2 diabetes, significantly reduces serum uric acid (SUA) concentration, a recent study has shown.

GLP-1 RAs help lower serum uric acid concentration

03 Aug 2022

Erlotinib + BSC fares better than BSC alone for gall bladder cancer

The addition of erlotinib to best supportive care (BSC) provided better survival benefit than BSC only in individuals with unresectable/metastatic gall bladder cancer (GBC) with poor performance status (PS), according to a phase II/III open-label study.

Erlotinib + BSC fares better than BSC alone for gall bladder cancer

Ibalizumab induces consistent HIV response when paired with partially active agents

Ibalizumab appears to be a promising treatment option in heavily treatment-experienced (HTE) patients with multidrug-resistant HIV-1 infections, yielding consistent efficacy outcomes even when used in combination with partially active agents, according to a study presented at the 24th International AIDS Conference (AIDS 2022).

Ibalizumab induces consistent HIV response when paired with partially active agents