News & Updates

$Ganaxolone drip safe, affords seizure control in patients with refractory status epilepticus$

Ganaxolone drip safe, affords seizure control in patients with refractory status epilepticus

07 Jul 2022

Treatment with intravenous ganaxolone induces rapid and durable seizure control in patients with refractory status epilepticus, while showing acceptable safety and tolerability, according to the results of an open-label phase II trial.

Ganaxolone drip safe, affords seizure control in patients with refractory status epilepticus

07 Jul 2022

Antithrombotics after a stroke: In whom, when and how?

06 Jul 2022 by

Large well-designed studies published in recent years point to an association of cerebral microbleeds (CMBs) with increased risks of intracerebral haemorrhage (ICH) and ischaemic stroke (IS). Although the association of CMBs with ICH is greater than with IS, the absolute incidence of IS is still higher than of ICH, implying that antithrombotics should not be routinely withheld for all patients with CMBs.

Antithrombotics after a stroke: In whom, when and how?

06 Jul 2022

Cognition linked to BMI, cerebral oxygenation in CKD

05 Jul 2022

Cognitive changes in patients with chronic kidney disease (CKD) appear to correlate with accompanying changes in body mass index (BMI) and cerebral regional oxygen saturation (rSO2), reports a recent longitudinal study.

Cognition linked to BMI, cerebral oxygenation in CKD

05 Jul 2022

Novel targeted therapy shows better response than chemo in BRAF V600-mutant paediatric LGG

05 Jul 2022 by

The combination of two targeted therapies, dabrafenib and trametinib, significantly improves the overall response rate (ORR) in paediatric patients with low-grade glioma (LGG) with BRAF V600 mutations compared with the combination of standard chemotherapy drugs, according to a study presented at ASCO 2022.

Novel targeted therapy shows better response than chemo in BRAF V600-mutant paediatric LGG

05 Jul 2022

Physiotherapy improves neuropathic pain biomarker profile

04 Jul 2022

Physiotherapeutic interventions, like exercise therapy and electro-acupuncture, appear to be effective at reducing the expression of neuropathic pain biomarkers, reveals a new systematic review.

Physiotherapy improves neuropathic pain biomarker profile

04 Jul 2022

Second-line antiseizure drug helps with toxin-related seizure in status epilepticus patients

02 Jul 2022

Some patients with benzodiazepine-refractory status epilepticus experience a toxin-related seizure, which can be successfully treated with a single dose of second-line antiseizure medication, according to a post hoc analysis of the Established Status Epilepticus Treatment Trial (ESETT).

Second-line antiseizure drug helps with toxin-related seizure in status epilepticus patients

02 Jul 2022

Routine cerebral magnetic resonance imaging catches low-grade pathologies in preemies

02 Jul 2022

The routine implementation of cerebral magnetic resonance imaging (cMRI) commonly detects low-grade abnormalities in extremely premature infants, such as low-grade intraventricular haemorrhage (IVH), white matter disease (WMD), and cerebellar injury (CBI), a new study has found.

Routine cerebral magnetic resonance imaging catches low-grade pathologies in preemies

02 Jul 2022

Ultra-high-dose methylcobalamin may reduce clinical progression in early-stage ALS

01 Jul 2022 by

Ultra-high-dose methylcobalamin (MeCbl) slowed functional decline in individuals with early-stage amyotrophic lateral sclerosis (ALS) with moderate progression, the JETALS* study has shown.

Ultra-high-dose methylcobalamin may reduce clinical progression in early-stage ALS

01 Jul 2022

High leucine tied to worse executive function in kids

30 Jun 2022 by

Executive function (EF) in children appears to be linked to the metabolome, particularly with the amino acid leucine, higher levels of which seem to worsen EF and memory in this population, according to a recent Singapore study.

High leucine tied to worse executive function in kids

30 Jun 2022

Oral contraceptive, hormone replacement therapy pose increased stroke risk

29 Jun 2022

The use of oral contraceptive and hormone replacement therapy may put women at heightened risk of stroke, especially within the first year of use, possibly due to immediate changes in haemostatic balance, according to a study.

Oral contraceptive, hormone replacement therapy pose increased stroke risk

29 Jun 2022

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Ganaxolone drip safe, affords seizure control in patients with refractory status epilepticus

Ganaxolone drip safe, affords seizure control in patients with refractory status epilepticus

Antithrombotics after a stroke: In whom, when and how?

Antithrombotics after a stroke: In whom, when and how?

Cognition linked to BMI, cerebral oxygenation in CKD

Cognition linked to BMI, cerebral oxygenation in CKD

Novel targeted therapy shows better response than chemo in BRAF V600-mutant paediatric LGG

Novel targeted therapy shows better response than chemo in BRAF V600-mutant paediatric LGG

Physiotherapy improves neuropathic pain biomarker profile

Physiotherapy improves neuropathic pain biomarker profile

Second-line antiseizure drug helps with toxin-related seizure in status epilepticus patients

Second-line antiseizure drug helps with toxin-related seizure in status epilepticus patients

Routine cerebral magnetic resonance imaging catches low-grade pathologies in preemies

Routine cerebral magnetic resonance imaging catches low-grade pathologies in preemies

Ultra-high-dose methylcobalamin may reduce clinical progression in early-stage ALS

Ultra-high-dose methylcobalamin may reduce clinical progression in early-stage ALS

High leucine tied to worse executive function in kids

High leucine tied to worse executive function in kids

Oral contraceptive, hormone replacement therapy pose increased stroke risk

Oral contraceptive, hormone replacement therapy pose increased stroke risk