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4-hydroxytamoxifen gel strikes out in ductal carcinoma in situ lesions

27 Oct 2023

Local transdermal therapy with 4-hydroxytamoxifen appears to be less effective than full-dose oral tamoxifen in terms of suppressing proliferation in ductal carcinoma in situ lesions for breast cancer prevention, according to a phase II study.

4-hydroxytamoxifen gel strikes out in ductal carcinoma in situ lesions

27 Oct 2023

COVID-19 vax in pregnancy not linked to adverse newborn, early infant outcomes

26 Oct 2023

Receipt of mRNA COVID-19 vaccination during pregnancy does not appear to increase the incidence of adverse newborn and early infant outcomes and may even be protective, according to a study.

COVID-19 vax in pregnancy not linked to adverse newborn, early infant outcomes

26 Oct 2023

Ritonavir-boosted nirmatrelvir protects older adults against post-COVID conditions

26 Oct 2023 by

Treatment with nirmatrelvir/ritonavir helps lower the incidence of post-COVID conditions (PCC) in older adults, according to a large study.

Ritonavir-boosted nirmatrelvir protects older adults against post-COVID conditions

26 Oct 2023

Histologic margin status predicts relapse in lentigo maligna melanoma

26 Oct 2023

Histologic margin status shows a robust association with progression for lentigo maligna melanoma, suggest the results of a recent study.

Histologic margin status predicts relapse in lentigo maligna melanoma

26 Oct 2023

Is colonic stenting advisable for acute malignant large bowel obstruction?

26 Oct 2023 by

Insertion of self-expandable metal stents (SEMS) for acute malignant large bowel obstruction (MBO) results in high technical and clinical success with a favourable safety profile, as shown in a recent Singapore study.

Is colonic stenting advisable for acute malignant large bowel obstruction?

26 Oct 2023

Assisted reproductive technology may raise risk of congenital anomalies in infants

26 Oct 2023

Children conceived with assisted reproductive technology (ART) appear to be at slightly increased risk for developing genitourinary abnormalities, according to a study.

Assisted reproductive technology may raise risk of congenital anomalies in infants

26 Oct 2023

Brentuximab vedotin fares well for CTCL in real-world study

26 Oct 2023 by

Interim findings from a prospective real-world study in Poland demonstrated favourable clinical outcomes and a tolerable safety profile for the CD30-directed antibody-drug conjugate brentuximab vedotin in patients with CD30-expressing cutaneous T-cell lymphoma (CTCL).

Brentuximab vedotin fares well for CTCL in real-world study

26 Oct 2023

One BPG dose may be enough to treat syphilis, regardless of HIV status

26 Oct 2023 by

Three doses of benzathine penicillin G (BPG) are not necessarily better than a single dose in the treatment of early syphilis in individuals with or without HIV infection, as shown in a study.

One BPG dose may be enough to treat syphilis, regardless of HIV status

26 Oct 2023

mRNA-1647 vaccine well tolerated regardless of CMV serostatus

26 Oct 2023 by

MRNA-1647, Moderna's investigational mRNA-based vaccine against cytomegalovirus (CMV), is well tolerated in healthy adults regardless of CMV serostatus, according to a study presented at IDWeek 2023.

mRNA-1647 vaccine well tolerated regardless of CMV serostatus

26 Oct 2023

Monoclonal antibody helps preserve muscle mass regardless of protein intake

25 Oct 2023 by

Treatment with bimagrumab appears to prevent muscle loss resulting from inadequate protein intake and increase muscle mass in the setting of enough protein intake, according to data from phase I and IIa studies.

Monoclonal antibody helps preserve muscle mass regardless of protein intake

25 Oct 2023

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4-hydroxytamoxifen gel strikes out in ductal carcinoma in situ lesions

4-hydroxytamoxifen gel strikes out in ductal carcinoma in situ lesions

COVID-19 vax in pregnancy not linked to adverse newborn, early infant outcomes

COVID-19 vax in pregnancy not linked to adverse newborn, early infant outcomes

Ritonavir-boosted nirmatrelvir protects older adults against post-COVID conditions

Ritonavir-boosted nirmatrelvir protects older adults against post-COVID conditions

Histologic margin status predicts relapse in lentigo maligna melanoma

Histologic margin status predicts relapse in lentigo maligna melanoma

Is colonic stenting advisable for acute malignant large bowel obstruction?

Is colonic stenting advisable for acute malignant large bowel obstruction?

Assisted reproductive technology may raise risk of congenital anomalies in infants

Assisted reproductive technology may raise risk of congenital anomalies in infants

Brentuximab vedotin fares well for CTCL in real-world study

Brentuximab vedotin fares well for CTCL in real-world study

One BPG dose may be enough to treat syphilis, regardless of HIV status

One BPG dose may be enough to treat syphilis, regardless of HIV status

mRNA-1647 vaccine well tolerated regardless of CMV serostatus

mRNA-1647 vaccine well tolerated regardless of CMV serostatus

Monoclonal antibody helps preserve muscle mass regardless of protein intake

Monoclonal antibody helps preserve muscle mass regardless of protein intake