News & Updates

Starting oestradiol therapy soon after menopause may be good for heart health

25 Mar 2020 by

Taking oestradiol therapy within 6 years after the start of menopause significantly delayed lipid plaque buildup in arterial walls — a leading cause of atherosclerosis, but such benefit was not seen when starting oestradiol a decade after menopause, reveals a secondary analysis of the ELITE* study presented at the recent EPI Lifestyle 2020 Scientific Sessions.

Starting oestradiol therapy soon after menopause may be good for heart health

25 Mar 2020

Is there a role for nerinetide following ischaemic stroke?

25 Mar 2020 by

The eicosapeptide nerinetide did not improve outcomes in patients with large vessel occlusion-related acute ischaemic stroke who underwent endovascular thrombectomy (EVT). However, patients not treated with alteplase appeared to derive some benefit, results from the multinational ESCAPE-NA1* trial showed.

Is there a role for nerinetide following ischaemic stroke?

25 Mar 2020

Rituximab an acceptable biologic option for RA-associated bronchiectasis

25 Mar 2020

The use of rituximab in the treatment of rheumatoid arthritis (RA)-associated bronchiectasis (BR) helps stabilize or improve pulmonary symptoms, with a more favourable respiratory survival over a 5-year follow-up as compared with tumour necrosis factor inhibitors (TNFi), according to a retrospective study.

Rituximab an acceptable biologic option for RA-associated bronchiectasis

25 Mar 2020

Nitroimidazole exposure may dampen efficacy of triple therapy in H. pylori infection

25 Mar 2020

Exposure to nitroimidazole appears to mitigate the efficacy of nitroimidazole-based triple regimen, but not quadruple therapy, in patients with Helicobacter pylori infection, results of a study have shown.

Nitroimidazole exposure may dampen efficacy of triple therapy in H. pylori infection

25 Mar 2020

Sprifermin keeps moving FORWARD in knee osteoarthritis treatment

25 Mar 2020 by

Post hoc results of the phase II FORWARD* study continued to reflect positive structural changes with the recombinant human fibroblast growth factor(FGF)-18 sprifermin, given the substantial dose-dependent increases in cartilage thickness gain and reductions in cartilage loss independent of location in the femorotibial joints (FTJ) of patients with knee osteoarthritis (OA).

Sprifermin keeps moving FORWARD in knee osteoarthritis treatment

25 Mar 2020

Metformin potentially cardioprotective in nondiabetic adults

25 Mar 2020 by

Treatment with metformin yields reductions in total and low-density lipoprotein cholesterol levels in individuals without diabetes, even providing an additional triglyceride-lowering effect among those with polycystic ovary syndrome (PCOS), according to the results of a meta-analysis.

Metformin potentially cardioprotective in nondiabetic adults

25 Mar 2020

Inclisiran lowers LDL levels in patients at high risk for ASCVD

25 Mar 2020 by

Treatment with inclisiran led to a significantly reduced low-density lipoprotein (LDL) cholesterol levels in patients with atherosclerotic cardiovascular disease (ASCVD), according to two phase III randomized clinical trials.

Inclisiran lowers LDL levels in patients at high risk for ASCVD

25 Mar 2020

Investigational HIV vaccine fails

24 Mar 2020 by

The National Institute of Allergy and Infectious Diseases (NIAID) recently made the decision to terminate the phase IIb/III HVTN 702 (Uhambo) trial that was investigating a vaccine to prevent HIV.

Investigational HIV vaccine fails

24 Mar 2020

Vonoprazan noninferior to lansoprazole for erosive oesophagitis in some Asians

24 Mar 2020 by

A phase III study has shown the noninferiority of the potassium-competitive acid blocker vonoprazan to the proton pump inhibitor (PPI) lansoprazole for the management of erosive oesophagitis (EO) in an Asian* cohort.

Vonoprazan noninferior to lansoprazole for erosive oesophagitis in some Asians

24 Mar 2020

Could prompt tranexamic acid treatment reduce ICH growth?

23 Mar 2020 by

Prompt treatment with tranexamic acid may reduce intracerebral haemorrhage (ICH) growth in patients with ongoing bleeding, though the timing of treatment appears to be key to improved outcomes, according to a study presented at ISC 2020.

Could prompt tranexamic acid treatment reduce ICH growth?

23 Mar 2020

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Starting oestradiol therapy soon after menopause may be good for heart health

Starting oestradiol therapy soon after menopause may be good for heart health

Is there a role for nerinetide following ischaemic stroke?

Is there a role for nerinetide following ischaemic stroke?

Rituximab an acceptable biologic option for RA-associated bronchiectasis

Rituximab an acceptable biologic option for RA-associated bronchiectasis

Nitroimidazole exposure may dampen efficacy of triple therapy in H. pylori infection

Nitroimidazole exposure may dampen efficacy of triple therapy in H. pylori infection

Sprifermin keeps moving FORWARD in knee osteoarthritis treatment

Sprifermin keeps moving FORWARD in knee osteoarthritis treatment

Metformin potentially cardioprotective in nondiabetic adults

Metformin potentially cardioprotective in nondiabetic adults

Inclisiran lowers LDL levels in patients at high risk for ASCVD

Inclisiran lowers LDL levels in patients at high risk for ASCVD

Investigational HIV vaccine fails

Investigational HIV vaccine fails

Vonoprazan noninferior to lansoprazole for erosive oesophagitis in some Asians

Vonoprazan noninferior to lansoprazole for erosive oesophagitis in some Asians

Could prompt tranexamic acid treatment reduce ICH growth?

Could prompt tranexamic acid treatment reduce ICH growth?