News &amp; Updates

Dyspnoea is associated with higher perceived stress in silica-exposed workers from the artificial stone benchtop industry at risk of silicosis, a permanent but preventable lung disease, suggests a study.

Dyspnoea may elevate stress in artificial stone benchtop industry workers

How effective are contraceptive counseling, provision interventions for women?

Contraceptive counseling and provision of services beyond usual care are both effective at improving contraceptive use without increasing sexually transmitted infections (STIs) or reducing condom use, results of a systematic review and meta-analysis have shown.

How effective are contraceptive counseling, provision interventions for women?

EMPRISE shows CV efficacy, safety of empagliflozin in routine care

The final analysis of the 5-year monitoring EMPRISE* programme presented at ADA 2022 demonstrated the cardiovascular (CV) efficacy of empagliflozin in patients with type 2 diabetes (T2D), with a safety profile that aligns with existing evidence.

EMPRISE shows CV efficacy, safety of empagliflozin in routine care

Infertility treatments tied to developmental delays at age 2 years

Infants conceived with the help of infertility treatments, such as ovulation induction (OI) and artificial insemination with the husband’s sperm (AIH), are more likely to experience developmental delays at 2 years of age, according to a recent Japan study. However, such delays appear to grow nonsignificant by 3.5 years of age.

Infertility treatments tied to developmental delays at age 2 years

Concomitant insulin may counter renoprotective effects of SGLT2is in T2D patients with CKD

Renal composite outcomes (RCO) appear to be less favourable among type 2 diabetes (T2D) patients with chronic kidney disease (CKD) treated with insulin and sodium-glucose cotransporter 2 inhibitors (SGLT2i), a recent Japan study has found.

Concomitant insulin may counter renoprotective effects of SGLT2is in T2D patients with CKD

16 Jun 2022

JAK inhibition with upadacitinib works well in nr-axSpA

Treatment with upadacitinib improves disease activity, pain, function, and quality of life (QoL) in patients with non-radiographic axial spondyloarthritis (nr-axSpA) in a study touted as the first to evaluate a Janus kinase (JAK) inhibitor for this condition.

JAK inhibition with upadacitinib works well in nr-axSpA

Fixed-dose albuterol/budesonide an effective rescue med in moderate-to-severe asthma

15 Jun 2022 by

A fixed-dose combination of albuterol and budesonide, delivered as needed, reduced the risk of severe exacerbations in patients with moderate-to-severe asthma inadequately controlled with corticosteroid maintenance therapy, according to results of the phase III MANDALA trial presented at ATS 2022.

Fixed-dose albuterol/budesonide an effective rescue med in moderate-to-severe asthma

15 Jun 2022

Exercise helps avoid hypoxia, preserve brain metabolism and cognition in OSA

By preventing hypoxia, exercise training can help improve the cerebral metabolic rate and cognitive function in patients with moderate to severe obstructive sleep apnoea (OSA), a recent study has found.

Exercise helps avoid hypoxia, preserve brain metabolism and cognition in OSA

SGLT2 inhibitors beneficial in Chinese patients with type 2 diabetes

15 Jun 2022 by

A Singapore study has reported good real-world experience with sodium-glucose co-transporter-2 (SGLT2) inhibitors, which are well tolerated and effective at improving blood sugar and lowering complications risk.

SGLT2 inhibitors beneficial in Chinese patients with type 2 diabetes

How effective is adjunctive dexmedetomidine for alcohol withdrawal in ICU patients?

In critically ill patients with alcohol withdrawal syndrome (AWS), adding dexmedetomidine to symptom-triggered benzodiazepines appears to cause no significant change in Clinical Institute Withdrawal Assessment for Alcohol (CIWA-Ar) scores from baseline compared to symptom-triggered therapy alone, a recent study has found.

How effective is adjunctive dexmedetomidine for alcohol withdrawal in ICU patients?