News &amp; Updates

The choice of stress ulcer prophylaxis strategy – proton pump inhibitor (PPI) or histamine-2 receptor blocker (H₂RB) – did not affect mortality within 90 days of admission to the intensive care unit (ICU), according to results of the PEPTIC* trial presented at the recent Critical Care Reviews Meeting (CCR20).

PPI, H2RB as stress ulcer prophylaxis in ICU yield similar mortality rate

Infliximab, adalimumab both effective in biologic-naive IBD patients

Use of adalimumab or infliximab in biologic-naïve patients with inflammatory bowel disease (IBD) delivers comparable rates of corticosteroid-free remission, as shown by a study presented at the Advances in Inflammatory Bowel Disease (AIBD) Conference 2019.

Infliximab, adalimumab both effective in biologic-naive IBD patients

Vedolizumab useful, safe for long-term treatment of inflammatory bowel disease

Most patients with moderately to severely active ulcerative colitis and Crohn’s disease on vedolizumab persist with their treatment for up to 5 years, according to a posthoc analysis of the phase III GEMINI long-term safety (LTS) study presented at the Advances in Inflammatory Bowel Diseases (AIBD) 2019 Annual Meeting.

Vedolizumab useful, safe for long-term treatment of inflammatory bowel disease

Lemborexant improves sleep onset, maintenance in older adults with insomnia

Treatment with lemborexant, a dual orexin receptor antagonist, significantly improves sleep onset and maintenance in older adults with insomnia disorder, according to the SUNRISE 1* trial.

Lemborexant improves sleep onset, maintenance in older adults with insomnia

Substance abuse ups risk of heart failure hospitalizations, readmissions

23 Jan 2020 by

Substance-abuse disorders (SADs) are not at all uncommon among patients with heart failure (HF), according to a study. Several SADs independently correlate with HF-related emergency department (ED) visits and hospitalizations.

Substance abuse ups risk of heart failure hospitalizations, readmissions

Tenofovir better than entecavir for minimizing HCC risk in HBV

Tenofovir disoproxil fumarate (TDF) for hepatitis B virus (HBV) infection suppresses hepatocellular carcinoma (HCC) risk better than entecavir, a new study has found.

Tenofovir better than entecavir for minimizing HCC risk in HBV

TURANDOT trials confirm efficacy of ontamalimab in inducing remission in UC patients

23 Jan 2020 by

The TURANDOT* and TURANDOT II** studies confirm the efficacy of the monoclonal immunoglobulin G2 anti-MAdCAM-1*** antibody ontamalimab to induce remission in patients with ulcerative colitis (UC).

TURANDOT trials confirm efficacy of ontamalimab in inducing remission in UC patients

Coffee consumption does not raise uric acid levels

Coffee drinkers do not appear to have elevated serum uric acid levels compared with nondrinkers, a study has found.

Coffee consumption does not raise uric acid levels