News &amp; Updates

Combination treatment with trabectedin and durvalumab appears to be promising in the treatment of patients with platinum-refractory ovarian carcinoma, shrinking tumour while having a manageable side effect profile, according to data from the phase Ib TRAMUNE trial.

Trabectedin–durvalumab combo shows antitumour activity in refractory ovarian carcinoma

10 May 2022

Vegetarian diet in early childhood poses risk of underweight

Children with a vegetarian diet are more likely to be underweight compared with those who have nonvegetarian diets, although their growth or biochemical nutrition outcomes are similar, according to a study.

Vegetarian diet in early childhood poses risk of underweight

Inflammatory markers in tears help detect COVID-19

Elevated levels of various proinflammatory cytokines in tears can indicate active SARS-CoV-2 infection and the presence of the virus in the conjunctiva, a recent study has found.

Inflammatory markers in tears help detect COVID-19

Early neurosurgery tied to better survival in spontaneous haemorrhagic stroke

Neurosurgery performed 2–4 hours after presenting to the emergency department (ED) seems to result in better survival outcomes in patients with spontaneous haemorrhagic stroke, reports a recent study.

Early neurosurgery tied to better survival in spontaneous haemorrhagic stroke

Ravulizumab shows rapid, sustained benefits for myasthenia gravis

Treatment with ravulizumab leads to rapid and sustained reductions in myasthenia gravis (MG) symptoms, according to the CHAMPION study presented at AAN 2022.

Ravulizumab shows rapid, sustained benefits for myasthenia gravis

Breast arterial calcification may indicate CVD risk in postmenopausal women

Breast arterial calcification (BAC), as viewed on screening mammograms, may suggest a risk of cardiovascular disease (CVD) in postmenopausal women, a recent US-based study showed.

Breast arterial calcification may indicate CVD risk in postmenopausal women

BNT162b2 prevents children from getting very sick but does not make them super immune

In the period of COVID-19 pandemic predominated by the milder yet highly transmissible Omicron variant, BNT162b2 vaccination of young children can shield them against severe infection. However, the antiviral armour afforded by this vaccine weakens over time, as reported in a recent study.

BNT162b2 prevents children from getting very sick but does not make them super immune

09 May 2022

Nutritional indices at admission predict mortality in ICU patients

Nutritional indices at admission are predictive of higher mortality rates in adult patients in the intensive care unit (ICU), reveals a recent study.

Nutritional indices at admission predict mortality in ICU patients

New chemo-free triplet regimen shows promise for endometrial cancer

A triplet regimen combining the PARP inhibitor olaparib with metronomic cyclophosphamide and metformin showed favourable signals for heavily pretreated women with advanced endometrial carcinoma, the phase I/II ENDOLA study suggests.

New chemo-free triplet regimen shows promise for endometrial cancer

09 May 2022

What drives persistent distress in COVID-19 frontliners?