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Amivantamab-lazertinib bests osimertinib in head-to-head trial on lung cancer
In the phase III MARIPOSA trial, the amivantamab-lazertinib cocktail outdid osimertinib as first-line (1L) treatment for EGFR-mutated, advanced non-small cell lung cancer (NSCLC).
Amivantamab-lazertinib bests osimertinib in head-to-head trial on lung cancer
08 Nov 2023Placebo effect delivers in open-angle glaucoma
Treatment with placebo is successful in patients with open-angle glaucoma or ocular hypertension, achieving lower intraocular pressure (IOP), compared with untreated control participants, reports a recent study.
Placebo effect delivers in open-angle glaucoma
07 Nov 2023Nirmatrelvir-ritonavir benefits persist against COVID
Management of most adults with COVID-19, particularly those with mild-to-moderate disease, is increasingly occurring in the outpatient setting due to the availability of effective treatment options.
Nirmatrelvir-ritonavir benefits persist against COVID
07 Nov 2023Rosuvastatin on par with atorvastatin in CAD
Rosuvastatin is as effective as atorvastatin for the composite outcome of all-cause death, myocardial infarction (MI), stroke, or any coronary revascularization at 3 years in adults with coronary artery disease (CAD), according to the secondary analysis of the LODESTAR trial.
Rosuvastatin on par with atorvastatin in CAD
06 Nov 2023Add-on immunotherapy prolongs survival in advanced endometrial cancer
In the treatment of patients with advanced or recurrent endometrial carcinoma, adding the PD-L1 inhibitor atezolizumab to chemotherapy helps lower the risk of progression or death, according to the phase III AtTEnd trial.
Add-on immunotherapy prolongs survival in advanced endometrial cancer
03 Nov 2023Enfortumab vedotin-pembrolizumab beats chemo as 1L Tx for bladder cancer
In the phase III EV-302/KEYNOTE-A39 trial, the combination of enfortumab vedotin and pembrolizumab (EV+P) had a significant survival advantage over chemotherapy in the first-line treatment of patients with locally advanced metastatic urothelial carcinoma (la/mUC).
Enfortumab vedotin-pembrolizumab beats chemo as 1L Tx for bladder cancer
03 Nov 2023Biomarker-driven therapies superior to standard care in breast cancer
Patients with breast cancer may gain greater therapeutic advantages from biomarker-driven than standard-of-care therapies, suggests a study.