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Investigational DP2 antagonist strikes out in eosinophilic asthma
The prostaglandin D2 receptor 2 (DP2) antagonist GB001 does not appear to significantly lower the risk of disease worsening in patients with moderate-to-severe eosinophilic asthma, according to data from a phase IIb trial.
Investigational DP2 antagonist strikes out in eosinophilic asthma
13 Mar 2022Vitamin D deficiency tied to severe COVID-19
A systematic review and meta-analysis of >8,000 adult and elderly patients with COVID-19 showed a positive association between vitamin D deficiency (ie, 25(OH)D <50 nmol/L) and severe COVID-19.
Vitamin D deficiency tied to severe COVID-19
13 Mar 2022Shorter antibiotic regimen enough in kids with pneumonia?
Children with non-severe community-acquired pneumonia (CAP) may benefit from a 5-day antibiotic regimen compared with the current standard regimen of 10 days, according to results of the US-based SCOUT-CAP trial.
Shorter antibiotic regimen enough in kids with pneumonia?
10 Mar 2022Delamanid-based regimens work against multidrug-resistant tuberculosis
The use of delamanid-containing regimens is safe and effective in the management of multidrug-resistant tuberculosis (MDR-TB), with high culture conversion and treatment success rates despite extensive resistance patterns, according to the results of a meta-analysis.
Delamanid-based regimens work against multidrug-resistant tuberculosis
10 Mar 2022Female sex, hypertension, number of initial symptoms tied to long COVID risk
The risk of developing long COVID is high among women, hypertensives, and those with a higher number of initial symptoms, and these associations are independent of disease severity and clinical course, a study has found.
Female sex, hypertension, number of initial symptoms tied to long COVID risk
09 Mar 2022Post-COVID sequelae conditions identified, could help establish definition
Patients diagnosed with COVID-19 could have an increased risk of certain conditions up to 120 days post-diagnosis, a finding which could help establish the definition of Post-Acute Sequelae of SARS-CoV-2 Infection (PASC), according to a study presented at CROI 2022.