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Diet with hyperinsulinaemic potential ups risk of breast cancer
Women with a dietary pattern contributing to hyperinsulinaemia and insulin resistance appear to be at increased risk of breast cancer, particularly estrogen-receptor (ER)-negative and human epidermal growth factor receptor 2 (HER2)-enriched tumours, reveals a study.
Diet with hyperinsulinaemic potential ups risk of breast cancer
15 Jan 2023PFS in relapsed/refractory CLL/SLL: Zanubrutinib triumphs over ibrutinib
The second-generation BTK* inhibitor zanubrutinib was superior to the standard-of-care ibrutinib in improving progression-free survival (PFS) among patients with relapsed/refractory chronic lymphocytic leukaemia (R/R CLL) or small lymphocytic lymphoma (SLL), according to results of the phase III ALPINE trial presented at ASH 2022.
PFS in relapsed/refractory CLL/SLL: Zanubrutinib triumphs over ibrutinib
15 Jan 2023KRAS G12C inhibitors show promise in metastatic colorectal and pancreatic cancers
The KRASG12C inhibitors, adagrasib and sotorasib, have shown promising antitumour activity in patients with heavily pretreated metastatic colorectal cancer (mCRC) and metastatic pancreatic cancer, respectively.
KRAS G12C inhibitors show promise in metastatic colorectal and pancreatic cancers
13 Jan 2023Recent hyperglycaemia helps detect pancreatic cancer early
Pancreatic cancer may be identified early if assessment will be steered towards the point of recent hyperglycaemia based on elevated HbA1c, suggests a retrospective cohort study, noting that such early detection may then improve survival in cancer patients.
Recent hyperglycaemia helps detect pancreatic cancer early
11 Jan 2023Meta-analysis: No link between PPI use and gastric cancer
Proton pump inhibitor (PPI) therapy does not appear to put individuals who require gastric acid suppression at increased risk of gastric cancer, according to a study.