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IBD patients at higher risk of Alzheimer’s disease
Inflammatory bowel disease (IBD) shows an independent relationship with the development of Alzheimer’s disease (AD), with such association being stronger in patients with Crohn’s disease (CD) than those with ulcerative colitis (UC), reveals a study.
Exergaming improves neuronal activity and executive function in older adults with dementia
Findings of a small randomized trial in older adults with moderate dementia suggest that exergaming may be associated with greater improvements in brain neuronal activity and enhanced executive function task performance than regular aerobic exercise.
Early addition of cerebrolysin to reperfusion therapy reduces haemorrhagic transformation after ischaemic stroke
A prospective, randomized, multicentre pilot study finds that early addition of cerebrolysin to reperfusion therapy is safe and significantly reduces the rate of haemorrhagic transformation (HT) after acute ischaemic stroke (AIS).
Frailty may portend cognitive decline
Initial frailty status appears to be a potential predictor of the occurrence of the composite of probable dementia and mild cognitive impairment, and this association is strengthened by intensive blood pressure control, as reported in a study.
Study supports apixaban use in AF patients with dementia
Anticoagulation therapy with apixaban yields lower rates of ischaemic stroke and intracranial and extracranial major bleeding compared with other oral anticoagulants (OACs) in patients with atrial fibrillation (AF), with the magnitude of benefit for major bleeding even greater for those who have dementia, according to a study.