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Response analysis further establishes tezepelumab benefit in severe uncontrolled asthma
Adolescents and adults with severe uncontrolled asthma while on inhaled corticosteroids (ICS) had greater responses to the human monoclonal antibody tezepelumab than placebo, according to prespecified exploratory results of the phase III NAVIGATOR trial.
Response analysis further establishes tezepelumab benefit in severe uncontrolled asthma
27 Jun 2022Infliximab, adalimumab biosimilars effective, safe in paediatric IBD
The use of biosimilars of infliximab (IFX) and adalimumab (ADA) is both safe and effective in children with inflammatory bowel disease (IBD), inducing high rates of failure-free survival with a low incidence of adverse events, according to a study presented at the 2022 Annual Meeting of the European Society for Paediatric Gastroenterology, Hepatology, and Nutrition (ESPGHAN 2022).
Infliximab, adalimumab biosimilars effective, safe in paediatric IBD
27 Jun 2022Diabetes, fertility treatment, family history up autism risk in infants
A recent Egypt study has identified several maternal and neonatal factors contributing to the risk of autism spectrum disorders (ASD) in infants, including the use of assisted fertility treatments, family medical history, and threatened abortion.
Diabetes, fertility treatment, family history up autism risk in infants
26 Jun 2022Oral dexamethasone trumps prednisolone for acute asthma attacks in kids
Oral dexamethasone proved more effective than oral prednisolone for the management of acute exacerbation of mild-to-moderate asthma in children, a study suggests.
Oral dexamethasone trumps prednisolone for acute asthma attacks in kids
24 Jun 2022Baricitinib delays, lowers frequency of flares in JIA
In patients with juvenile idiopathic arthritis (JIA) with insufficient response to conventional synthetic (cs) or biologic (b) disease-modifying antirheumatic drugs (DMARDs), the JAK*1/2 selective inhibitor baricitinib reduced the frequency and delayed time to disease flares, according to a phase III trial presented at EULAR 2022.
Baricitinib delays, lowers frequency of flares in JIA
23 Jun 2022NAFLD linked to heightened type 2 diabetes risk
Children with nonalcoholic fatty liver disease (NAFLD) are at an increased risk of type 2 diabetes, a study reports. Other risk factors for T2D include severity of liver histology, body mass index, and female sex.