News & Updates

Investigational drug gains upper hand over placebo in reducing CDI recurrence rates

20 May 2022 by

SER-109, an investigational oral microbiome therapeutic, achieves superiority over placebo in reducing recurrent Clostridioides difficile infection (CDI) rates, according to updated findings from the phase III ECOSPOR-III trial.

Investigational drug gains upper hand over placebo in reducing CDI recurrence rates

20 May 2022

5-strain probiotic blend improves functional gastrointestinal symptoms

19 May 2022 by

Treatment with a newly developed probiotic blend made up of five strains (Bl-04, Bi-07, HN019, NCFM, and Lpc-37) is safe and leads to better gastrointestinal (GI) well-being as early as day 14, with sustained improvements up to day 30, a recent study has shown. Few adverse events resulting in discontinuation have been reported.

5-strain probiotic blend improves functional gastrointestinal symptoms

19 May 2022

Endoscopic papillary large balloon dilation reduces relapse in recurrent common bile duct stones

15 May 2022

Stone recurrence arises following traditional endoscopic retrograde cholangiopancreatography (ERCP) in nearly half of the patients with recurrent common bile duct stone (CBDS) during long-term follow-up, reports a recent study.

Endoscopic papillary large balloon dilation reduces relapse in recurrent common bile duct stones

15 May 2022

Urgency tied to poorer quality of life, ups hospitalization risk in UC patients

15 May 2022

Urgency, or the immediate need to defecate, in patients with ulcerative colitis (UC) is an independent predictor of compromised quality of life (QoL) and future risk of hospitalizations, corticosteroid use, and colectomy, suggests a study.

Urgency tied to poorer quality of life, ups hospitalization risk in UC patients

15 May 2022

Long-term aspirin use lowers HCC risk in chronic HBV patients

14 May 2022

Use of aspirin in the long term appears to markedly reduce the risk of hepatocellular carcinoma (HCC) in patients with chronic hepatitis B virus (HBV), a study has shown.

Long-term aspirin use lowers HCC risk in chronic HBV patients

14 May 2022

Radiologic features predict more necrosectomies in walled-off necrosis

11 May 2022

Several features of computed tomography (CT) imaging are significantly predictive of undergoing at least two necrosectomy sessions for patients with walled-off pancreatic necrosis (WON), suggest the results of a recent study.

Radiologic features predict more necrosectomies in walled-off necrosis

11 May 2022

Educating about nocebo effects helps improve tolerance to tricyclic antidepressants

10 May 2022

A short intervention that addresses the nocebo (negative placebo) effect appears to improve tolerance of tricyclic antidepressants (TCAs), which are commonly used to treat disorders of gut-brain interaction (DGBI), a study has shown.

Educating about nocebo effects helps improve tolerance to tricyclic antidepressants

10 May 2022

Norfloxacin prevents bacterial infections in patients with liver failure

10 May 2022 by

Primary norfloxacin prophylaxis is both safe and effective in preventing bacterial infections in patients with acute-on-chronic liver failure (ACLF), a study has shown.

Norfloxacin prevents bacterial infections in patients with liver failure

10 May 2022

Rectal evacuation disorders tied to poor bowel preparation in chronic constipation patients

10 May 2022

Outlet dysfunction is associated with suboptimal bowel preparation and decreased cecal intubation, among others, in patients with chronic constipation undergoing colonoscopy, reveals a study.

Rectal evacuation disorders tied to poor bowel preparation in chronic constipation patients

10 May 2022

Adebrelimab plus chemo almost doubles OS, triples PFS in extensive-stage SCLC

06 May 2022 by

Adding adebrelimab to chemotherapy improves survival outcomes over chemotherapy alone in patients with extensive-stage small cell lung cancer (SCLC) in the phase III CAPSTONE-1 study presented at AACR 2022. This brings hope to SCLC patients with limited treatment options and poor prognoses.

Adebrelimab plus chemo almost doubles OS, triples PFS in extensive-stage SCLC

06 May 2022

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Investigational drug gains upper hand over placebo in reducing CDI recurrence rates

Investigational drug gains upper hand over placebo in reducing CDI recurrence rates

5-strain probiotic blend improves functional gastrointestinal symptoms

5-strain probiotic blend improves functional gastrointestinal symptoms

Endoscopic papillary large balloon dilation reduces relapse in recurrent common bile duct stones

Endoscopic papillary large balloon dilation reduces relapse in recurrent common bile duct stones

Urgency tied to poorer quality of life, ups hospitalization risk in UC patients

Urgency tied to poorer quality of life, ups hospitalization risk in UC patients

Long-term aspirin use lowers HCC risk in chronic HBV patients

Long-term aspirin use lowers HCC risk in chronic HBV patients

Radiologic features predict more necrosectomies in walled-off necrosis

Radiologic features predict more necrosectomies in walled-off necrosis

Educating about nocebo effects helps improve tolerance to tricyclic antidepressants

Educating about nocebo effects helps improve tolerance to tricyclic antidepressants

Norfloxacin prevents bacterial infections in patients with liver failure

Norfloxacin prevents bacterial infections in patients with liver failure

Rectal evacuation disorders tied to poor bowel preparation in chronic constipation patients

Rectal evacuation disorders tied to poor bowel preparation in chronic constipation patients

Adebrelimab plus chemo almost doubles OS, triples PFS in extensive-stage SCLC

Adebrelimab plus chemo almost doubles OS, triples PFS in extensive-stage SCLC