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Venetoclax + chemo disappoints in double-hit lymphoma trial
In patients with double-hit lymphoma (DHL), the addition of the BCL2 inhibitor venetoclax to a chemoimmunotherapeutic regimen comprising DA-EPOCH-R* led to excess treatment-related mortality compared with DA-EPOCH-R alone, according to the initial results of the phase II/III Alliance A051701 trial.
Venetoclax + chemo disappoints in double-hit lymphoma trial
27 Dec 2021
Asian-derived polygenic risk scores boost risk stratification for breast cancer
Drawing from the largest available studies of Asian breast cancer patients, a recent Singapore study has developed polygenic risk scores (PRS) that can help improve the risk stratification of women of Asian ancestry.
Asian-derived polygenic risk scores boost risk stratification for breast cancer
27 Dec 2021
Lumateperone improves depression symptoms in bipolar disorder
Treatment with 42-mg lumateperone daily leads to significant improvement in depression symptoms, with no serious safety issues, among patients with major depressive episodes associated with both bipolar I and II disorders, a study has shown.