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Whole-exome sequencing enhances diagnosis in young CRC patients
Whole-exome sequencing (WES) can improve diagnosis rates in young colorectal cancer (CRC) patients who show no pathogenic variants in mismatch repair (MMR) genes or in the adenomatous polyposis coli (APC) gene, reports a recent study.
Whole-exome sequencing enhances diagnosis in young CRC patients
09 Mar 2022Medication risks an acceptable trade-off for cure of IBS symptoms
Patients with irritable bowel syndrome (IBS) are willing to take on significant medication risks in exchange for a permanent cure of their symptoms, a study has found.
Medication risks an acceptable trade-off for cure of IBS symptoms
07 Mar 2022Traditional dietary advice most preferred for IBS
Traditional dietary advice, gluten-free diet, and low FODMAP diet are all effective dietary approaches to reducing symptoms in patients with irritable bowel symptom (IBS), but traditional dietary advice is the pick of the bunch in terms of cost and convenience, according to a team of UK-based researchers.
Traditional dietary advice most preferred for IBS
07 Mar 2022Weight change in adults tied to colorectal adenoma risk
Weight loss during adulthood, particularly among overweight or obese individuals, is associated with a reduction in the risk of developing distal colorectal adenomas – a precursor to colorectal cancer, whereas weight gain increased its risk, according to findings from the PLCO* Cancer Screening Trial.
Weight change in adults tied to colorectal adenoma risk
04 Mar 2022Universal HCV screening in pregnancy: A step toward reducing transmission?
Universal screening for hepatitis C virus (HCV) in pregnant individuals resulted in improved detection and a potential reduction in perinatal transmission, according to a study presented at CROI 2022.
Universal HCV screening in pregnancy: A step toward reducing transmission?
01 Mar 2022Allopurinol use, dose escalation do not increase mortality in gout patients with CKD
In patients with gout and concurrent chronic kidney disease (CKD), the risk of mortality does not seem to increase with initiation of allopurinol, achieving target serum urate (SU) level with allopurinol, or treatment dose escalation, a study has shown.
Allopurinol use, dose escalation do not increase mortality in gout patients with CKD
01 Mar 2022KEYNOTE-394 a win for Asians with advanced HCC
Combining pembrolizumab with best supportive care (BSC) improved survival and response when used as second-line therapy in Asians with advanced hepatocellular carcinoma (HCC).