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Sotrovimab may reduce COVID-19 disease progression
The pan-sarbecovirus monoclonal antibody sotrovimab appears to reduce the risk of COVID-19 disease progression in high-risk patients, according to interim results of the phase III COMET-ICE* trial.
Sotrovimab may reduce COVID-19 disease progression
23 Nov 2021
Subgroup findings boost dupilumab benefit for CRSwNP, comorbid asthma
In post hoc analyses of the phase III SINUS-24 and SINUS-52 trials, the monoclonal antibody dupilumab continued to render improvements for patients with severe chronic rhinosinusitis with nasal polyps (CRSwNP), as well as among those with comorbid asthma regardless of asthma characteristics.
Subgroup findings boost dupilumab benefit for CRSwNP, comorbid asthma
18 Nov 2021
Dapagliflozin in COVID-19: Outcomes consistent regardless of kidney status
Secondary analysis of the DARE-19* trial presented at ASN Kidney Week 2021 has shown that the effect of dapagliflozin in patients with cardiometabolic risk factors hospitalized with COVID-19 is consistent regardless of kidney disease status.
Dapagliflozin in COVID-19: Outcomes consistent regardless of kidney status
17 Nov 2021
Asthma, high BMI, older age up risk of small airway dysfunction
Small airway disfunction can lead to increased airway resistance and visible computed tomography (CT) changes, according to a study. Furthermore, this disease is more common among individuals with advanced age, high body mass index (BMI), childhood cough, and asthma.
Asthma, high BMI, older age up risk of small airway dysfunction
14 Nov 2021
Symptomatic COVID-19 at pregnancy end tied to increased complications in mothers, infants
Expectant mothers with symptomatic COVID-19 upon hospital admission for delivery had a higher risk of emergency complications surrounding delivery, according to a small retrospective study from the US presented at Anesthesiology 2021. Furthermore, infants born to symptomatic mothers were more likely to require intensive care unit (ICU) admission or respiratory support.