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High-dose semaglutide improves glucose metabolism outcomes in overweight/obese patients with T2D
Treatment with a higher dose of semaglutide led to significantly improved glucose metabolism outcomes in patients with overweight/obesity and type 2 diabetes (T2D) compared with a lower dose of semaglutide or placebo, according to the STEP* 2 trial presented at EASD 2021.
High-dose semaglutide improves glucose metabolism outcomes in overweight/obese patients with T2D
27 Oct 2021Durvalumab + tremelimumab + chemo: A new first-line SoC for mNSCLC?
The combination of durvalumab, tremelimumab, and chemotherapy in the first-line setting improved progression-free survival (PFS) and overall survival (OS) in patients with metastatic non-small-cell lung cancer (mNSCLC), according to results of the phase III POSEIDON trial.
Durvalumab + tremelimumab + chemo: A new first-line SoC for mNSCLC?
26 Oct 2021Atrophic gastritis, PPI use amplify EC risk in immunocompetent patients
In immunocompetent patients admitted at a community hospital, comorbidities such as advanced gastric cancer and atrophic gastritis (AG), as well as treatment with proton pump inhibitors (PPI), seem to aggravate the risk of developing oesophageal candidiasis (EC), a recent study has found.
Atrophic gastritis, PPI use amplify EC risk in immunocompetent patients
26 Oct 2021Everolimus helps fight recurrent thymic neuroendocrine neoplasia
Treatment with everolimus appears to have beneficial effects on recurrent thymic neuroendocrine neoplasia (NEN), particularly well-differentiated tumours, with patients having a low Ki-67 index more likely to have a better outcome with the drug, as shown in a small study.
Everolimus helps fight recurrent thymic neuroendocrine neoplasia
26 Oct 2021Therapeutic heparin may reduce death, bleeding risks in moderate COVID-19
Use of therapeutic heparin does not appear to significantly reduce the death, mechanical ventilation, or intensive care unit (ICU) admission in hospitalized patients with moderate COVID-19 and increased D-dimer levels, reveals a study. However, it is associated with a significantly lower chances of all-cause death and reduced risk of major bleeding.
Therapeutic heparin may reduce death, bleeding risks in moderate COVID-19
26 Oct 2021Minimally invasive surgery feasible for nonendometroid endometrial cancers
Minimally invasive surgery for nonendometrioid endometrial cancer performs comparably as open surgery, yielding similar survival outcomes, a recent study has found.
Minimally invasive surgery feasible for nonendometroid endometrial cancers
26 Oct 2021Mendelian analysis links coffee drinking to lower kidney stone risk
Genetic data provide evidence that drinking coffee or caffeine intake in high amounts may cause a reduction in the risk of kidney stones, as shown in a study.