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Proteomic profiling of COPD may lead to new treatment strategies
A recent study has provided a detailed proteomic profile that identified proteins associated with the pathogenesis and disease progression of chronic obstructive pulmonary disease (COPD), which can then help in the creation of platform to develop effective new treatment strategies.
Proteomic profiling of COPD may lead to new treatment strategies
17 Oct 2021One in 10 Singaporeans affected by asthma
A recent multi-ethnic Singapore study confirms that asthma is a common disease, affecting more than 10 percent of adults, especially former smokers and those with high body mass index (BMI). Asthma is also associated with worse health-related quality of life (HRQoL), making it a substantial public health concern.
One in 10 Singaporeans affected by asthma
15 Oct 2021Lenzilumab reduces likelihood of survival without ventilation in COVID-19 patients
In hospitalized COVID-19 patients, treatment with the novel GM-CSF* neutralizing monoclonal antibody lenzilumab led to a significant improvement in survival without invasive mechanical ventilation (SWOV), findings from the phase III LIVE-AIR study suggest.
Lenzilumab reduces likelihood of survival without ventilation in COVID-19 patients
14 Oct 2021Novel RT-PCR may help detect SARS-CoV-2 mutations tied to VoC
The Spike single-nucleotide polymorphism (SNP) assay, a single-reaction multiplex real-time RT-PCR, provides fast, inexpensive, and sensitive detection of specific mutations associated with SARS-CoV-2 variants of concern (VoC), according to data presented at ID Week 2021.
Novel RT-PCR may help detect SARS-CoV-2 mutations tied to VoC
12 Oct 2021SGLT2 inhibitors help ward off asthma
Patients on sodium-glucose co-transporter (SGLT) 2 inhibitors are less likely to develop asthma compared with those on dipeptidyl peptidase (DPP)-4 inhibitors and glucagon-like peptide-1 receptor agonists (GLP-1RAs), a study has found.
SGLT2 inhibitors help ward off asthma
12 Oct 2021Households, not schools, major SARS-CoV-2 transmission route among HK children
Households, and not schools, are the major route of coronavirus disease 2019 (COVID-19) transmission for those ≤18 years of age, according to a cross-sectional study of nearly 400 Hong Kong children and youths who contracted COVID-19 in 2020.
Households, not schools, major SARS-CoV-2 transmission route among HK children
12 Oct 2021Recovered mothers transfer SARS-CoV-2 antibodies to newborns
A Hong Kong study demonstrates vertical transfer of antibodies against acute respiratory syndrome coronavirus 2 (SARS-CoV-2) to babies whose mothers have recovered from coronavirus disease 2019 (COVID-19).
Recovered mothers transfer SARS-CoV-2 antibodies to newborns
12 Oct 2021Tamibaroterone inhalable dry powder shows broad-spectrum activity against SARS-CoV-2, MERS and H1N1
Researchers from the University of Hong Kong (HKU) have developed a dry powder formulation of tamibaroterone, which displays broad-spectrum antiviral activity against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), Middle East respiratory syndrome coronavirus (MERS-CoV), and pandemic 2009 influenza A virus (H1N1), when delivered intranasally or through inhalation in mouse and hamster models.
Tamibaroterone inhalable dry powder shows broad-spectrum activity against SARS-CoV-2, MERS and H1N1
12 Oct 2021Early convalescent plasma infusion does not prevent COVID-19 progression
An infusion of convalescent plasma, obtained via blood donation from individuals who have recovered from COVID-19, did not prevent disease progression in high-risk outpatients who presented within 7 days of COVID-19 symptom onset, results of the phase III US-based SIREN-C3PO* study showed.