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Perioperative durvalumab-based regimen improves outcomes in resectable NSCLC
In individuals with resectable non-small-cell lung cancer (NSCLC), the addition of perioperative durvalumab to neoadjuvant chemotherapy improved pathologic complete response (pCR) and event-free survival (EFS), findings from the AEGEAN study have shown.
Perioperative durvalumab-based regimen improves outcomes in resectable NSCLC
12 Jun 2023Add-on myoinositol helps with menstrual period regularity in women with PCOS
In the treatment of women with polycystic ovary syndrome (PCOS), adding myoinositol to metformin provides further benefits for improving the regularity of menstrual cycle, with subsequent gains in quality of life, according to a study.
Add-on myoinositol helps with menstrual period regularity in women with PCOS
12 Jun 2023Upfront osimertinib matches sequential treatment for prolonging survival in EGFR-mutant NSCLC
Patients with nonsmall cell lung cancer (NSCLC) harbouring EGFR mutation appear to experience similar survival outcomes with either frontline osimertinib therapy or sequential treatment approach of gefitinib followed by osimertinib, although upfront osimertinib leads to a significant reduction in the risk of brain progression, as shown in the results of the APPLE trial presented at ELCC 2023.
Upfront osimertinib matches sequential treatment for prolonging survival in EGFR-mutant NSCLC
10 Jun 2023Nonchemotherapy doublet shows therapeutic potential in PD-1/PD-L1 inhibitor‒resistant NSCLC
Combination treatment with eftilagimod alpha plus pembrolizumab has shown promising signal of activity against metastatic nonsmall cell lung cancer (NSCLC) in patients resistant to PD-1/PD-L1 inhibitors, as shown in the updated results of the phase II TACTI-002 study.
Nonchemotherapy doublet shows therapeutic potential in PD-1/PD-L1 inhibitor‒resistant NSCLC
09 Jun 2023Pioglitazone–SGLT2 inhibitor combo delivers for primary CV prevention in diabetes
Combination treatment with pioglitazone plus a sodium-glucose co-transporter 2 (SGLT2) inhibitor helps reduce the risk of developing major adverse cardiovascular events (MACE) and heart failure in individuals with type 2 diabetes mellitus (T2DM) who have no history of cardiovascular disease (CV), as reported in a study.
Pioglitazone–SGLT2 inhibitor combo delivers for primary CV prevention in diabetes
09 Jun 2023Vaccination uptake among kids in SG: Flu shots lag behind pneumococcal vax
Not enough children in Singapore are getting vaccinated against influenza, whereas the number of those who are receiving pneumococcal shots has steadily increased over time.
Vaccination uptake among kids in SG: Flu shots lag behind pneumococcal vax
08 Jun 2023Pazopanib plus chemo improves response but not survival in advanced ovarian cancer
Treatment with pazopanib combined with chemotherapy leads to better overall response rate (ORR) in patients with recurrent or persistent ovarian cancer but falls short of improving survival, reveals a study. In addition, the combination therapy contributes to an increase in several adverse events (AEs).
Pazopanib plus chemo improves response but not survival in advanced ovarian cancer
08 Jun 2023First-line cemiplimab improves survival in unresectable NSCLC
First-line treatment with cemiplimab, either as monotherapy or in combination with platinum-based chemotherapy, provides clinical benefits to patients with unresectable locally advanced nonsmall cell lung cancer (NSCLC) who are not candidates for definitive concurrent chemoradiation, as shown by long-term follow-up data from EMPOWER-Lung studies.