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Antigliadin IgG spots IBS patients who benefit from gluten-free diet
Some patients with irritable bowel syndrome (IBS) may achieve symptom reduction, particularly diarrhoea, on a gluten-free diet, and who these patients are may be identified by using the antigliadin immunoglobulin G (IgG) as a biomarker, according to a study.

Bevacizumab reduces need for vitrectomy in PDR patients with vitreous haemorrhage
Intravitreal bevacizumab (IVB) injections induce short-lived visual benefit but ease the need for vitrectomy in proliferative diabetic retinopathy (PDR) patients with vitreous haemorrhage (VH) who had undergone prior complete panretinal photocoagulation (PRP), a recent study has found.

Accelerated cognitive decline risk with diabetes higher in women than men
Among patients with type 2 diabetes (T2D), women appear to be at greater risk of accelerated cognitive decline than men, as reported in a study. This risk increase can be partly explained by depressive symptoms being greater among women.

Rapid test for COVID-19 not so perfect
Panbio, a rapid antigen test for SARS-CoV-2, has good specificity but limited sensitivity, as shown in a study. As such, all negative tests have to be confirmed with RT-PCR, especially in the presence of related symptoms, in settings with high community infection rate, and in cases of direct contact with confirmed COVID-19 patients.

Mirtazapine of no benefit for agitated behaviours in dementia
Results of a randomized, double-blind, placebo-controlled trial show no benefit with mirtazapine, given with normal clinical care, for treatment of clinically significant agitation in patients with dementia compared with placebo, with a potentially higher mortality observed with the use of mirtazapine.

Noninvasive tests predict liver-related events in early alcohol-related liver disease
In patients with early-stage alcohol-related liver disease, transient elastography (TE), the enhanced liver fibrosis test (ELF), and 2-dimensional shear-wave elastography (2D-SWE) can reliably predict the risk of symptomatic liver events, a recent study has found.



