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Oral antibiotics not inferior to IV-only therapy in blood, bone infections
Use of oral antibiotics in the treatment of osteomyelitis, bacteraemia, and infective endocarditis results in shorter hospital stay, has a better safety profile, and appears to be similarly effective when compared to intravenous (IV)-only therapy, a recent study has shown.

Omicron more stable than ancestral strain on surfaces, resistant to neutralizing mAbs
The Omicron variant of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is more stable than the ancestral strain on various smooth and porous surfaces and demonstrates marked resistance to neutralizing monoclonal antibodies (mAbs), researchers from the University of Hong Kong (HKU) have reported.

COVID-19 vaccine antibodies wane within 6 months in older adults
Older adults in long-term care facilities see a rapid drop in antibody titres over the first 6 months after the second dose of the BNT162b2 vaccine for the coronavirus disease 2019 (COVID-19), reports a recent study.

Lower resilience tied to poorer medication adherence in glaucoma patients
The COVID-19 pandemic has worsened the adherence to ocular hypotensive medication among patients with primary open-angle glaucoma (POAG), according to a study. Such reduction is potentially driven by lower psychometric measures of resilience and more confrontational coping strategies.

Booster COVID-19 vacc cuts breakthrough infection risk, particularly in individuals with no immune dysfunction
Receipt of a booster dose of the COVID-19 vaccine reduces the risk of breakthrough COVID-19 infections* compared to full vaccination only, particularly among individuals without immunosuppressed/compromised conditions (ISC), according to a US study presented at CROI 2022.




