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Short-course, high-dose gatifloxacin gets a pass in multidrug-resistant TB with caveat
A short-term treatment regimen based on high-dose gatifloxacin appears to be effective against multidrug- or rifampicin-resistant tuberculosis (TB) but at the cost of increased severe adverse drug reactions, as shown in a study.

MRNA COVID-19 vaccines weaker in patients with autoimmune systemic diseases
Patients with autoimmune systemic diseases (ASD) are less likely to produce an immune response following inoculation with mRNA vaccines against the coronavirus disease 2019 (COVID-19), according to a recent study.

Pandemic boom in wearable device use bares disparities in healthcare access
Despite the uptick in digital cardiology care during the coronavirus disease 2019 (COVID-19) pandemic, several key barriers to wearable device use remain, including high costs and limited technology knowledge, according to a recent study.

Do mask wearing, physical distancing, handwashing really protect against COVID-19?
Handwashing, mask wearing, and physical distancing effectively reduce the transmission of SARS-CoV-2 and the incidence of COVID-19, suggest the results of a systematic review and meta-analysis.

Urinary proadrenomedullin predicts severity of community-acquired pneumonia in children
Urinary proadrenomedullin (proADM)/creatinine (Cr) ratio measured at the time of emergency department visit appears predictive of the development of severe outcomes in children with community-acquired pneumonia (CAP), with stronger discriminatory performance in radiographic disease, suggests a recent study.

Child abuse increased during COVID-19 lockdown
Child abuse rates appear to have increased during the lockdowns imposed to control COVID-19 transmission, according to a study from the US presented at the 2021 American Academy of Pediatrics National Conference & Exhibition (AAP 2021).

Childhood cancers often misdiagnosed as TB, leads to more deaths
Cancer is frequently misdiagnosed as tuberculosis (TB) in children due to the clinical and radiologic overlap of the two diseases, which then contributes to increased mortality in this population, reveals a recent study.

