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Maternal TDF, infant HBV vax, HBIg-free strategy prevent infant hep B

Maternal TDF, infant HBV vax, HBIg-free strategy prevent infant hep B

01 Apr 2025 byAudrey Abella

In the absence of infant hepatitis B immune globulin (HBIg), maternal tenofovir disoproxil fumarate (TDF) prophylaxis combined with infant hepatitis B virus (HBV) immunization provide sufficient protection against HBV infection in infants, findings from the iTAP-2 study suggest. However, the risk of infection was not demonstrably below 2 percent.

01 Apr 2025
More syphilis cases picked up with universal vs targeted ED screening

More syphilis cases picked up with universal vs targeted ED screening

24 Mar 2025 byJairia Dela Cruz

Relying on targeted screening models for syphilis in emergency departments (EDs) leaves a substantial number of active cases undetected, new research shows.

24 Mar 2025
Prenatal BPG delivery: 9-day treatment interval linked to higher risk of congenital syphilis

Prenatal BPG delivery: 9-day treatment interval linked to higher risk of congenital syphilis

23 Mar 2025

When treating late latent syphilis during pregnancy, extending the interval between benzathine penicillin G (BPG) doses to 9 days may put newborns at risk of congenital infection relative to 6–8-day intervals, according to new research.

23 Mar 2025
Ensitrelvir safe, effective in preventing COVID-19 in households

Ensitrelvir safe, effective in preventing COVID-19 in households

21 Mar 2025 byStephen Padilla

Treatment with ensitrelvir among household contacts (HHC) of index patients (IP) with COVID-19 within 72 h after the onset of IP symptoms demonstrates efficacy and an acceptable safety profile as postexposure prophylaxis (PEP) in SCORPIO-PEP, a phase III placebo-controlled trial.

21 Mar 2025