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Faecal microbiota transplantation (FMT) with standardized anaerobic cultivated human intestinal microbiome is safe but does not appear to be efficacious in patients with systemic sclerosis experiencing lower gastrointestinal (GI) tract symptoms, according to a phase II study.
Dual immunotherapy with checkpoint inhibitors nivolumab and ipilimumab works better to slow disease progression in patients with microsatellite instability-high or mismatch repair-deficient (MSI-H/dMMR) metastatic colorectal cancer (mCRC) when compared with single-agent nivolumab, as shown in the phase III CheckMate 8HW trial.
Underweight, central obesity, and grade 3 obesity are all associated with a higher risk of death in adults, reveals a study. On the other hand, peripheral fat has an inverse association with mortality.
A meta-analysis suggests that a family history of developmental dysplasia of the hip (DDH) and breech presentation in pregnancy contribute to a substantial increase in the risk DDH in infants within the 3 months of life.
Pregnant women who use glucocorticoids may put their offspring at risk of certain mental disorders, according to a large cohort study.
Extreme heat is a health hazard to older people living with Alzheimer's disease and dementia (ADRD), having been associated with increased hospitalizations in a recent study.
Individuals on a pro-inflammatory diet are at greater risk of developing chronic kidney disease (CKD), suggests a study, noting the importance of adopting an anti-inflammatory diet to prevent CKD.
Preliminary data from an observational case–control study have shown that selexipag is safe and effective in the treatment of systemic sclerosis vasculopathy, particularly digital ulcers (DUs) and Raynaud phenomenon (RP).
Hospitalized preterm infants who received routine 2-month vaccinations were more likely to experience an apnoea episode within 48 hours than those who did not receive any vaccinations, according to a recent study.
In the treatment of patients with acute ischaemic stroke who underwent intravenous thrombolysis (IVT), remote ischaemic conditioning does not appear to increase the chances of achieving excellent functional outcome, according to a study.
