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Early prostacyclin therapy beneficial to infants with congenital diaphragmatic hernia

13 Apr 2023

In neonates with congenital diaphragmatic hernia, early treatment with prostacyclin appears to reduce the need for extracorporeal life support in the postnatal period, according to a study.

Early prostacyclin therapy beneficial to infants with congenital diaphragmatic hernia

13 Apr 2023

Lebrikizumab helps clear skin of teens with moderate-to-severe atopic dermatitis

12 Apr 2023 by

Treatment with lebrikizumab with or without topical corticosteroids (TCS) results in clinical improvement among adolescents with moderate-to-severe atopic dermatitis (AD), according to a study presented at the recent AAD 2023.

Lebrikizumab helps clear skin of teens with moderate-to-severe atopic dermatitis

12 Apr 2023

$Antiosteoporosis agents help prevent postfracture death$

Antiosteoporosis agents help prevent postfracture death

12 Apr 2023

Use of antiosteoporotic medication, particularly a long-acting regimen, appears to reduce postfracture mortality, according to a population-based study.

Antiosteoporosis agents help prevent postfracture death

12 Apr 2023

Topical JAK inhibitor scores big in CHE

12 Apr 2023 by

Treatment with the investigational, topical pan-JAK inhibitor delgocitinib cream led to significantly greater improvements in efficacy outcomes compared with the vehicle cream in moderate-to-severe chronic hand eczema (CHE) in the pivotal phase III DELTA 1 trial, offering a rational strategy for targeted therapy.

Topical JAK inhibitor scores big in CHE

12 Apr 2023

Melatonin lowers risk of postoperative delirium

11 Apr 2023

For adults undergoing surgery, melatonin appears to help reduce the likelihood of postoperative delirium, according to the results of a meta-analysis.

Melatonin lowers risk of postoperative delirium

11 Apr 2023

How does dapagliflozin affect cardiac function, hormonal responses to exercise?

11 Apr 2023

Growth hormone (GH), compared with catecholamines, appears to be a better facilitator for the change from glucose to fatty acid metabolism following SGLT2 inhibitor use during exercise, reveals a study.

How does dapagliflozin affect cardiac function, hormonal responses to exercise?

11 Apr 2023

Ripretinib improves survival in advanced gastrointestinal stromal tumours

11 Apr 2023 by

Treatment with ripretinib provides a prolonged clinical and radiological benefit in patients with advanced gastrointestinal stromal tumours (GIST) within the expanded access program (EAP) in the UK, as shown in a study presented at the ESMO Sarcoma and Rare Cancers Congress 2023 in Lugano, Switzerland.

Ripretinib improves survival in advanced gastrointestinal stromal tumours

11 Apr 2023

Trabectedin plus radiotherapy well tolerated in patients with myxoid liposarcoma

11 Apr 2023

A phase II nonrandomized trial of trabectedin in combination with radiotherapy for the treatment of myxoid liposarcoma has failed to meet its endpoint, although this treatment combination appears to be well tolerated in patients.

Trabectedin plus radiotherapy well tolerated in patients with myxoid liposarcoma

11 Apr 2023

Sarecycline effective for acne vulgaris in patients with skin of colour

11 Apr 2023 by

Sarecycline demonstrated efficacy for the treatment of moderate-to-severe facial acne vulgaris in patients with skin of colour, according to a post hoc analysis of two phase III trials presented at AAD 2023.

Sarecycline effective for acne vulgaris in patients with skin of colour

11 Apr 2023

Upadacitinib delivers sustained PRO improvements in AD

10 Apr 2023 by

Data presented at AAD 2023 underpin the potential of upadacitinib, a selective Janus kinase inhibitor, to provide long-term improvements in patient-reported outcomes (PROs; skin symptoms, sleep, and quality of life [QoL]) in individuals with moderate-to-severe atopic dermatitis (AD).

Upadacitinib delivers sustained PRO improvements in AD

10 Apr 2023

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Early prostacyclin therapy beneficial to infants with congenital diaphragmatic hernia

Early prostacyclin therapy beneficial to infants with congenital diaphragmatic hernia

Lebrikizumab helps clear skin of teens with moderate-to-severe atopic dermatitis

Lebrikizumab helps clear skin of teens with moderate-to-severe atopic dermatitis

Antiosteoporosis agents help prevent postfracture death

Antiosteoporosis agents help prevent postfracture death

Topical JAK inhibitor scores big in CHE

Topical JAK inhibitor scores big in CHE

Melatonin lowers risk of postoperative delirium

Melatonin lowers risk of postoperative delirium

How does dapagliflozin affect cardiac function, hormonal responses to exercise?

How does dapagliflozin affect cardiac function, hormonal responses to exercise?

Ripretinib improves survival in advanced gastrointestinal stromal tumours

Ripretinib improves survival in advanced gastrointestinal stromal tumours

Trabectedin plus radiotherapy well tolerated in patients with myxoid liposarcoma

Trabectedin plus radiotherapy well tolerated in patients with myxoid liposarcoma

Sarecycline effective for acne vulgaris in patients with skin of colour

Sarecycline effective for acne vulgaris in patients with skin of colour

Upadacitinib delivers sustained PRO improvements in AD

Upadacitinib delivers sustained PRO improvements in AD