News & Updates

Epinephrine, given either at standard or high dose or in combination with vasopressin during out-of-hospital cardiac arrest (OHCA) resuscitation, leads to more favourable return of spontaneous circulation (ROSC) and survival to hospital admission but not survival to discharge or functional outcome, according to a study.

Antibiotic prophylaxis with vancomycin plus gentamicin alone for primary inflatable penile prosthesis surgery results in a higher risk of infection compared to nonstandard antibiotic regimens, suggests a recent study. On the other hand, antifungal use appears to reduce infection risk.

Treatment with the nonpurine xanthine oxidase inhibitor tigulixostat leads to a significant reduction in serum uric acid (sUA) levels while having an acceptable safety profile, as shown in data from the multicentre, double-blind, parallel-group, dose-finding phase II CLUE trial.

New drug applications approved by US FDA as of 16-31 January 2023 which includes New Molecular Entities (NMEs) and new biologics. It does not include Tentative Approvals. Supplemental approvals may have occurred since the original approval date.