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One-time sigmoidoscopy fends off colorectal cancer risk for up to 2 decades

02 Aug 2024 by

Once-only screening with flexible sigmoidoscopy appears to provide prolonged protection against colorectal cancer (CRC), reducing both incidence and mortality rates for up to 2 decades, according to the updated results of the UK Flexible Sigmoidoscopy Screening Trial (UKFSST).

02 Aug 2024

TOPAZ-1 3-year data reflect long-term survival benefit with durvalumab-chemo in BTC

31 Jul 2024 by

In the 3-year updated analysis of the phase III TOPAZ-1 study, the combination of durvalumab and gemcitabine-cisplatin (GC) chemotherapy continues to deliver an overall survival (OS) benefit in individuals with biliary tract cancer (BTC).

31 Jul 2024

AI predicts pancreatic cancer risk in diabetic patients

26 Jul 2024

Machine learning models can predict patients with new-onset diabetes who are at greater risk for developing pancreatic cancer, a study has shown.

26 Jul 2024

Is it safe for coeliac disease patients to take antiobesity drugs?

25 Jul 2024

Patients with coeliac disease (CD) on a gluten-free diet and are treated with anti obesity medications (AOMs) show comparable weight loss outcomes to those without CD, reports a study.

25 Jul 2024

Link between beverage intake, inflammatory cytokines may pave way for dietary interventions

24 Jul 2024

Understanding the relationship between beverage consumption and circulating inflammatory cytokines may help inform new targets for treatment, suggests a study.

24 Jul 2024

Curcumin cuts hepatic fat content in NASFL

23 Jul 2024

Supplementation with curcumin helps lower hepatic fat content in patients with nonalcoholic simple fatty liver (NASFL), driven by improvements in gut microbiota-dependent bile acid metabolism and Takeda G protein-coupled receptor 5 (TGR5) activation, a study has found.

23 Jul 2024

Benralizumab facilitates complete withdrawal of OGCs more than mepolizumab in EGPA

22 Jul 2024 by

Benralizumab offers more sustained and earlier elimination of oral GCs vs mepolizumab in patients with relapsing or refractory EGPA, suggests a post hoc analysis of the MANDARA study presented at EULAR 2024

22 Jul 2024

JAK inhibitors for autoimmune disease may confer protection against AMD

20 Jul 2024 by

The use of Janus kinase (JAK) inhibitors in the treatment of major autoimmune diseases appears to reduce the risk of age-related macular degeneration (AMD) for people above 40 years of age, according to a study.

20 Jul 2024

$Bisphosphonates cut fracture risk in older cirrhosis patients$

Bisphosphonates cut fracture risk in older cirrhosis patients

17 Jul 2024

Older patients with cirrhosis who are taking bisphosphonates appear to have a reduced incidence of fractures overall, according to a study.

17 Jul 2024

GLP-1RA treatment for T2DM may lower risk of surgery in inflammatory bowel disease

16 Jul 2024

Use of glucagon-like peptide-1 receptor agonist (GLP-1RA) appears to reduce the risk of inflammatory bowel disease (IBD)-related surgery in patients with type 2 diabetes mellitus (T2DM) and concomitant ulcerative colitis (UC) or Crohn’s disease (CD), according to a retrospective study.