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Long-term teduglutide improves intestinal absorption in children with SBS

09 Jun 2023

Treatment with teduglutide for 48 weeks results in increased intestinal absorption and decreased parenteral nutrition (PN) dependency in children with short bowel syndrome (SBS)-related intestinal failure (IF), as shown in a study.

Long-term teduglutide improves intestinal absorption in children with SBS

09 Jun 2023

Physical fitness protective against IBD risk in the young

08 Jun 2023

Children and adolescents with better cardiorespiratory endurance appear to have a reduced risk of inflammatory bowel disease (IBD), as shown in a study.

Physical fitness protective against IBD risk in the young

08 Jun 2023

Coeliac disease prevalent in patients with liver disorder

07 Jun 2023

Coeliac disease (CeD) appears to be common in patients with cryptogenic cirrhosis or cryptogenic hypertransaminasaemia, suggests a study, noting that these individuals must be considered high-risk groups for CeD.

Coeliac disease prevalent in patients with liver disorder

07 Jun 2023

Tofacitinib safe, effective in UC, but response fades after dose reduction

06 Jun 2023 by

Treatment with tofacitinib is both safe and effective in a real-world setting, as shown in a Canada study, in which a third of patients with ulcerative colitis (UC) achieved clinical remission with few serious adverse events. However, nearly half of them have lost response following dose de-escalation, and this is only partially recaptured with re-escalation.

Tofacitinib safe, effective in UC, but response fades after dose reduction

06 Jun 2023

Genetically predicted depression linked to multiple gastrointestinal disorders

31 May 2023

Genetic predisposition to major depressive disorder has the potential to increase the risk of gastrointestinal disorders such as gastroesophageal reflux disease (GERD), irritable bowel syndrome (IBS), peptic ulcer disease, and nonalcoholic fatty liver disease (NAFLD), according to the results of a Mendelian randomization study.

Genetically predicted depression linked to multiple gastrointestinal disorders

31 May 2023

Cancer incidence uncommon among low-risk pancreatic cysts during extended surveillance

31 May 2023

Low-risk branch duct intraductal papillary mucinous neoplasms (BD-IPMNs) appear to have a positive outlook, with the results of a recent meta-analysis showing that the incidence of advanced neoplasia during extended surveillance is low.

Cancer incidence uncommon among low-risk pancreatic cysts during extended surveillance

31 May 2023

Subgroup analysis CONFIRMs telipressin potential for treating HRS, alcoholic hepatitis

30 May 2023 by

In individuals with hepatorenal syndrome (HRS) compounded by alcoholic hepatitis (AH), treatment with the synthetic, long-acting vasopressin analogue terlipressin led to the achievement of verified HRS reversal, a subgroup analysis of the phase III CONFIRM trial has shown.

Subgroup analysis CONFIRMs telipressin potential for treating HRS, alcoholic hepatitis

30 May 2023

New data fortify obeticholic acid role in NASH treatment

29 May 2023 by

In the new analysis of the REGENERATE trial, the FXR* agonist obeticholic acid (OCA) was generally well tolerated and demonstrated a favourable safety profile in patients with nonalcoholic steatohepatitis (NASH).

New data fortify obeticholic acid role in NASH treatment

29 May 2023

Sofosbuvir/velpatasvir effective, safe for paediatric HCV

25 May 2023 by

The direct-acting antiviral (DAA) sofosbuvir/velpatasvir (SOF/VEL) was effective and safe for the treatment of chronic hepatitis C virus (HCV) infection in individuals aged 6–18 years, the PANDAA-PED study has shown.

Sofosbuvir/velpatasvir effective, safe for paediatric HCV

25 May 2023

Vedolizumab prevents postop CD recurrence: new indication likely

24 May 2023 by

Patients with resected Crohn’s disease (CD) who were treated with the gut-selective α4β7-integrin inhibitor vedolizumab were less likely to have endoscopic signs of recurrence compared with placebo in the Reprevio study presented at DDW 2023.

Vedolizumab prevents postop CD recurrence: new indication likely

24 May 2023

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Long-term teduglutide improves intestinal absorption in children with SBS

Long-term teduglutide improves intestinal absorption in children with SBS

Physical fitness protective against IBD risk in the young

Physical fitness protective against IBD risk in the young

Coeliac disease prevalent in patients with liver disorder

Coeliac disease prevalent in patients with liver disorder

Tofacitinib safe, effective in UC, but response fades after dose reduction

Tofacitinib safe, effective in UC, but response fades after dose reduction

Genetically predicted depression linked to multiple gastrointestinal disorders

Genetically predicted depression linked to multiple gastrointestinal disorders

Cancer incidence uncommon among low-risk pancreatic cysts during extended surveillance

Cancer incidence uncommon among low-risk pancreatic cysts during extended surveillance

Subgroup analysis CONFIRMs telipressin potential for treating HRS, alcoholic hepatitis

Subgroup analysis CONFIRMs telipressin potential for treating HRS, alcoholic hepatitis

New data fortify obeticholic acid role in NASH treatment

New data fortify obeticholic acid role in NASH treatment

Sofosbuvir/velpatasvir effective, safe for paediatric HCV

Sofosbuvir/velpatasvir effective, safe for paediatric HCV

Vedolizumab prevents postop CD recurrence: new indication likely

Vedolizumab prevents postop CD recurrence: new indication likely