News & Updates
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Second-line avelumab works against dMMR/MSI metastatic colorectal cancer
Treatment with the immune checkpoint inhibitor avelumab in the second-line setting confers survival and disease control benefits in patients with deficient mismatch repair and/or microsatellite instability (dMMR/MSI) metastatic colorectal cancer (mCRC) when compared with standard treatment, with a favourable safety profile, according to the results of the phase II SAMCO-PRODIGE 54 trial.
Early gestational diabetes treatment modest at best in preventing adverse neonatal outcomes
Treatment of gestational diabetes before 20 weeks’ gestation appears to lead to a modestly lower incidence of a composite of adverse neonatal outcomes as compared with no-immediate treatment, with no substantial differences noted for pregnancy-related hypertension or neonatal lean body mass, as reported in a study.
Uncomplicated UTI: Choosing antibiotics based on resistance rates helps prevent treatment failure
In the treatment of individuals with uncomplicated urinary tract infection (UTI), the use of antibiotics with lower reported resistance rates such as amoxicillin-clavulanate and nitrofurantoin (AC + N) lowers the rate of treatment failure, as shown in a study from Singapore.
GLP-1 RA, with or without SGLT2 inhibitors, prevents cardiac events in T2D
Treatment with the glucagon-like peptide-1 receptor agonist (GLP-1 RA) albiglutide results in fewer cardiovascular events, irrespective of sodium-glucose cotransporter-2 (SGLT2) inhibitor use, among patients with type 2 diabetes (T2D) and cardiovascular disease, according to the post hoc analysis of Harmony Outcomes*.
Frequent nut intake delays cognitive decline in older adults
Eating nuts on a regular basis provides neuroprotective benefits to older adults who are overweight or obese, have metabolic syndrome, and are predisposed to memory loss or confusion, results of a cohort study have shown.
