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Weight-loss surgery works for patients with compensated cirrhosis

28 Dec 2020

Patients with compensated cirrhosis appear to benefit from bariatric surgery, which leads to sustained weight loss and stable hepatic function on long-term follow-up, a study has found.

Weight-loss surgery works for patients with compensated cirrhosis

28 Dec 2020

UDCA for primary sclerosing cholangitis may lower biliary tract cancer risk

22 Dec 2020 by

Patients with primary sclerosing cholangitis (PSC) who are treated with ursodeoxycholic acid (UDCA) may have a lower risk of liver transplantation, all-cause death, or biliary tract cancer, according to a study from Japan.

UDCA for primary sclerosing cholangitis may lower biliary tract cancer risk

22 Dec 2020

Phase II trial shows potential of antidiabetic drug for NASH

22 Dec 2020 by

A greater proportion of individuals with biopsy-confirmed nonalcoholic steatohepatitis (NASH) and fibrosis had NASH resolution with subcutaneous semaglutide, a GLP-1* receptor agonist approved for the treatment of type 2 diabetes (T2D), a phase II study has shown.

Phase II trial shows potential of antidiabetic drug for NASH

22 Dec 2020

Liver enzyme elevations in COVID-19 secondary to other conditions

08 Dec 2020 by

The elevations in liver enzymes that occur in patients with COVID-19 may be due to other conditions and not as a direct result of COVID-19, according to a poster presented at the AASLD 2020 Liver Meeting.

Liver enzyme elevations in COVID-19 secondary to other conditions

08 Dec 2020

Neonatal cholestasis underpowered to detect portal hypertension in kids with AAT deficiency

08 Dec 2020

While the need for liver transplantation is not urgent and the risk of death is low, portal hypertension nevertheless disrupts growth measures in children with alpha-1-antitrypsin (AAT) deficiency, a recent study has shown.

Neonatal cholestasis underpowered to detect portal hypertension in kids with AAT deficiency

08 Dec 2020

Aplastic anaemia with underlying hepatitis leads to worse survival in kids

07 Dec 2020

Aplastic anaemia in children appears to lead to worse outcomes when associated with hepatitis, a recent Taiwan study has found. Vaccination against the hepatitis B virus (HBV) may have additional value in this population.

Aplastic anaemia with underlying hepatitis leads to worse survival in kids

07 Dec 2020

Hexavalent, pneumococcal vaccine update included in national immunisation schedule

05 Dec 2020 by

The Malaysian National Immunisation Programme (NIP) will now include a hexavalent combination DTaP-IPV-HiB-HepB vaccine and a pneumococcal vaccine.

Hexavalent, pneumococcal vaccine update included in national immunisation schedule

05 Dec 2020

Portal hypertension persistent in over half of HCV patients even after SVR

28 Nov 2020

Clinically significant portal hypertension may persist for weeks in about half of patients with hepatitis C virus (HCV)-related cirrhosis, even after sustained virological response (SVR) has been achieved, a new study has found. This may indicate that risk of decompensation remains.

Portal hypertension persistent in over half of HCV patients even after SVR

28 Nov 2020

Lanifibranor efficacy in NASH evident in diabetics and non-diabetics

27 Nov 2020 by

The efficacy of lanifibranor in reducing histological markers of non-alcoholic steatohepatitis (NASH) is comparable in patients with and without type 2 diabetes (T2D), according to the phase IIb NATIVE study presented as a poster at AASLD 2020.

Lanifibranor efficacy in NASH evident in diabetics and non-diabetics

27 Nov 2020

Seladelpar improves histologic, biochemical responses in NASH patients

27 Nov 2020 by

Use of the potent and selective PPARδ* agonist seladelpar led to improvements in histologic responses and liver chemistry in patients with biopsy-confirmed nonalcoholic steatohepatitis (NASH), a phase II study has shown.

Seladelpar improves histologic, biochemical responses in NASH patients

27 Nov 2020

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Weight-loss surgery works for patients with compensated cirrhosis

Weight-loss surgery works for patients with compensated cirrhosis

UDCA for primary sclerosing cholangitis may lower biliary tract cancer risk

UDCA for primary sclerosing cholangitis may lower biliary tract cancer risk

Phase II trial shows potential of antidiabetic drug for NASH

Phase II trial shows potential of antidiabetic drug for NASH

Liver enzyme elevations in COVID-19 secondary to other conditions

Liver enzyme elevations in COVID-19 secondary to other conditions

Neonatal cholestasis underpowered to detect portal hypertension in kids with AAT deficiency

Neonatal cholestasis underpowered to detect portal hypertension in kids with AAT deficiency

Aplastic anaemia with underlying hepatitis leads to worse survival in kids

Aplastic anaemia with underlying hepatitis leads to worse survival in kids

Hexavalent, pneumococcal vaccine update included in national immunisation schedule

Hexavalent, pneumococcal vaccine update included in national immunisation schedule

Portal hypertension persistent in over half of HCV patients even after SVR

Portal hypertension persistent in over half of HCV patients even after SVR

Lanifibranor efficacy in NASH evident in diabetics and non-diabetics

Lanifibranor efficacy in NASH evident in diabetics and non-diabetics

Seladelpar improves histologic, biochemical responses in NASH patients

Seladelpar improves histologic, biochemical responses in NASH patients