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Metformin shows knee OA pain-relieving potential
Metformin, a common medication for diabetes, appears to produce a moderate reduction in knee pain and stiffness for overweight or obese individuals with symptomatic knee osteoarthritis (OA), as shown in the results of a randomized clinical trial.

LHRH analogues vs tE2 patches: Which work best for prostate cancer?
The use of transdermal oestradiol (tE2) or oestrogen patches helps suppress testosterone and prostate-specific antigen (PSA) in men with locally advanced prostate cancer, with similar efficacy to that of luteinizing hormone-releasing hormone (LHRH) analogues, reports a study presented at EAU 2025.

SC vs IV pembrolizumab: Which route is better for metastatic NSCLC?
In patients with treatment-naive metastatic nonsmall cell lung cancer (NSCLC), subcutaneous (SC) pembrolizumab (pembro) demonstrates comparable efficacy to that of intravenous (IV) pembro as regards overall exposure and trough concentration, reports a study presented at ELCC 2025.

Neoadjuvant chemo plus durvalumab improves survival in NSCLC
The addition of durvalumab to neoadjuvant chemotherapy with cisplatin and docetaxel results in better survival rates among patients with resectable nonsmall cell lung cancer (NSCLC), according to a study presented at ELCC 2025.





