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COVID-19 vaccine perception poor among SG drivers
A substantial proportion of transport drivers in Singapore had poor vaccine perception, were hesitant to receive the COVID-19 vaccine, and were unwilling to receive the third dose (booster shot) despite the high vaccination coverage in the city-state, a cross-sectional pilot study reports.

Valaciclovir suppresses Epstein-Barr virus in COPD patients
Treatment with valaciclovir leads to efficacious suppression of Epstein-Barr virus (EBV), having the potential to reduce the sputum inflammatory cell infiltrate, in patients with chronic obstructive pulmonary disease (COPD), according to data from the EViSCO study.

Long COVID: What are the risk and protective factors?
A population-based, multicentre study finds female gender, transportation-, logistics- or discipline-related occupation, living with domestic workers, smoking, poor or very poor self-perceived health status, ≥3 chronic diseases, chronic medication use, and critical severity of COVID-19 to be associated with severe long COVID, while prior receipt of ≥2 doses of COVID-19 vaccines serves as a protective factor.

Remdesivir cuts mortality in COVID-19 patients requiring no or low-flow oxygen
In a systematic review and individual patient data meta-analysis, the broad-spectrum antiviral agent remdesivir reduced mortality in adult patients hospitalized for COVID-19 who did not require oxygen support or only required low-flow supplementation when the need for oxygen arose.

HK data: SGLT2 inhibitors cut risks of respiratory and renal diseases in T2DM
Sodium-glucose cotransporter 2 (SGLT2) inhibitors reduce the risks of respiratory and renal diseases vs dipeptidyl peptidase-4 (DPP-4) inhibitors in patients with type 2 diabetes mellitus (T2DM), researchers from the University of Hong Kong (HKU) have reported.

How to differentiate COVID-19 pneumonia from influenza and bacterial pneumonia on CT?
Arched bridge and/or vacuole signs on CT may support a diagnosis of COVID-19 pneumonia and assist in differentiation from influenza and bacterial pneumonia, a retrospective study by the Chinese University of Hong Kong has revealed.



