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Odevixibat improves pruritus, reduces bile acids in children with ALGS

13 Dec 2022 by

Treatment with odevixibat, a potent, selective IBAT* inhibitor, significantly improved pruritus and reduced serum bile acid levels in children with Alagille syndrome (ALGS), according to the ASSERT** trial presented at The Liver Meeting 2022.

Odevixibat improves pruritus, reduces bile acids in children with ALGS

13 Dec 2022

High-dose erythropoietin of little benefit to preemies with intraventricular haemorrhage

12 Dec 2022

The use of high-dose erythropoietin in the treatment of preterm infants with intraventricular haemorrhage (IVH) does not appear to produce improvements in neurological outcomes, according to a study.

High-dose erythropoietin of little benefit to preemies with intraventricular haemorrhage

12 Dec 2022

Preterm birth tied to poorer right ventricular remodeling

11 Dec 2022

In children with hypoplastic left heart syndrome, preterm birth appears to be associated with poor right ventricular (RV) remodeling parameters and lower transplant-free survival rates, a new study has found.

Preterm birth tied to poorer right ventricular remodeling

11 Dec 2022

E. coli, S. agalactiae afflict most infants with invasive bacterial infections

10 Dec 2022

From 2006 to 2020, the most common invasive bacterial infections (IBIs) among infants <3 months of age are S. agalactiae, E. coli, and S. aureus, reveals a recent study in Korea. In addition, an increasing trend of S. agalactiae has been seen.

E. coli, S. agalactiae afflict most infants with invasive bacterial infections

10 Dec 2022

Which factors raise mortality risk in neonates CRAB sepsis?

09 Dec 2022

In neonates with carbapenem-resistant Acinetobacter baumannii (CRAB) sepsis, factors such as congenital heart disease, clinical risk index for babies (CRIB) II score ≥9, shock, and severe thrombocytopaenia are associated with the risk of death, reveals a recent study.

Which factors raise mortality risk in neonates CRAB sepsis?

09 Dec 2022

Bacteraemia, UTI not uncommon in paediatric renal transplant recipients

08 Dec 2022

A few paediatric renal transplant recipients who presented with suspected infection within 2 years of transplant were diagnosed with bacteraemia or urinary tract infections (UTIs) or both, reports a study. Evaluations are highly variable, with a third of visits without urine cultures obtained.

Bacteraemia, UTI not uncommon in paediatric renal transplant recipients

08 Dec 2022

Minimally invasive surgery safer but less effective than open surgery in children with DRE

07 Dec 2022

In the treatment of children with drug-resistant epilepsy (DRE), minimally invasive magnetic resonance-guided laser interstitial thermal therapy is associated with lower rate of seizure freedom at 1 year but has the advantage of lower complication rates and shorter hospitalization as compared with open surgery, as shown in a study.

Minimally invasive surgery safer but less effective than open surgery in children with DRE

07 Dec 2022

Singapore’s youth endure high rates of bullying

07 Dec 2022 by

Peer victimization, or bullying, appears to be highly prevalent among youth, according to a recent Singapore study. In turn, bullying aggravates depressive symptoms and worsens quality of life.