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Shorter flare duration best indicator of treatment success in gout
Patients with gout consider flare duration, flare frequency, and pain severity when thinking about treatment efficacy over time, according to a study. Of these factors, shorter flare duration is deemed to be the most common indicator of successful treatment.

App-delivered mindfulness training eases anxiety
Mindfulness training (MT) delivered through an app (Unwinding Anxiety) significantly alleviates anxiety, a study has shown. Increases in psychological nonreactivity and reductions in worry mediate the effects of this app, which suggests a specific targeting of reinforcement learning.

Antidepressant therapy: To continue or not?
In individuals who had been on antidepressant therapy for at least 9 months but felt well enough to consider discontinuing, the risk of relapse of depression was greater among those who stopped vs those who carried on with their current regimen, the ANTLER* trial has shown.

Losing weight lowers risk of hypertensive disorders of pregnancy
Lifestyle interventions or bariatric surgery leading to preconceptional weight loss effectively reduces the risk of hypertensive disorders of pregnancy (HDP), such as pregnancy-induced hypertension (PIH) and pre-eclampsia (PE), reports a recent meta-analysis.

Is prior allergy a deal-breaker for COVID-19 vacc?
A large prospective, observational study has suggested that while individuals with a history of high-risk allergy may have an increased risk of allergic reactions following receipt of a messenger RNA (mRNA) COVID-19 vaccine, they are still able to receive both vaccine doses.




