News &amp; Updates

Longer and poorer-quality sleep may promote higher brachial-ankle pulse wave velocity (baPWV) among patients with hypertension, a recent study suggests.

Longer, poor sleep linked to higher arterial stiffness in hypertensive adults

Good sleep needed to maintain optimal nutritional status in older adults

Sleep disorders usually go hand in hand with malnutrition in older adults, according to a study, highlighting the importance that this population get good sleep quality and sufficient amount of it in order to maintain good nutritional status.

Good sleep needed to maintain optimal nutritional status in older adults

Original New Drug Application Approvals by US FDA (01 - 15 December 2020)

New drug applications approved by US FDA as of 01 - 15 December 2020 which includes New Molecular Entities (NMEs) and new biologics. It does not include Tentative Approvals. Supplemental approvals may have occurred since the original approval date.

Original New Drug Application Approvals by US FDA (01 - 15 December 2020)

Niraparib improves PFS in Chinese patients with ovarian cancer

15 Dec 2020 by

An individualized dosing regimen of niraparib, a potent inhibitor of PARP 1/2, resulted in significantly improved progression-free survival (PFS) among Chinese patients with platinum-sensitive recurrent (PSR) ovarian cancer, according to a subgroup analysis of the NORA* study presented at ESMO Asia 2020.

Niraparib improves PFS in Chinese patients with ovarian cancer

Durable polymer noninferior to biodegradable drug-eluting stent in ACS

Durable polymer drug-eluting stents (DES) appeared noninferior to biodegradable polymer DES in patients with acute coronary syndrome (ACS) with stenosis scheduled for percutaneous coronary intervention (PCI), results of the Korea-based HOST-Reduce-Polytech-ACS* trial showed. However, the device-oriented outcome appeared to side with the durable stent.

Durable polymer noninferior to biodegradable drug-eluting stent in ACS

Cannabis has ceiling concentration for efficacy

Tetrahydrocannabinol (THC) is effective in reducing pain, but only up to a certain plasma concentration, beyond which it appears to magnify pain, according to a new study.

Cannabis has ceiling concentration for efficacy

What are the barriers to self-care of CKD?

Lack of knowledge among patients, insufficient communication between doctors and patients, and lack of motivation are stumbling blocks to self-care of chronic kidney disease (CKD) in Singapore, while trust for doctors and family support can turn the tide around, a local study finds.

What are the barriers to self-care of CKD?

Can common BP-lowering drugs keep breast cancer in check?

Angiotensin receptor blockers, used to treat high blood pressure (BP), appear to confer dose-dependent survival benefits on breast cancer patients when taken either prior to or after diagnosis, a study has found.

Can common BP-lowering drugs keep breast cancer in check?

NOACs lower renal function decline in AF patients

A prescription of nonvitamin K antagonist (VKA) oral anticoagulants (NOACs) in patients with atrial fibrillation (AF) leads to a lower renal function worsening compared to those receiving VKAs, suggests a recent study, adding that such effect is partially lost in diabetic patients.

NOACs lower renal function decline in AF patients

ARTEMIS 1: Bimatoprost implant noninferior to timolol in lowering IOP

Bimatoprost implant of either 10- or 15-μg dose strength is noninferior to timolol through week 12 in patients with open-angle glaucoma (OAG) or ocular hypertension (OHT), according to the results of the phase III trial ARTEMIS 1.

ARTEMIS 1: Bimatoprost implant noninferior to timolol in lowering IOP