News & Updates

CEA may predict better survival with targeted therapy in mCRC

01 Sep 2020 by

A lower baseline carcinoembryonic antigen (CEA) is associated with better overall survival (OS) in patients receiving treatment with encorafenib plus cetuximab with or without binimetinib for BRAF V600E-mutant metastatic CRC (mCRC), according to a subanalysis of BEACON CRC presented during the 2020 ESMO GI Meeting.

CEA may predict better survival with targeted therapy in mCRC

01 Sep 2020

Faecal calprotectin levels shed light on Crohn’s disease course

01 Sep 2020 by

For patients with Crohn’s disease, normalization of faecal calprotectin levels within 12 months of diagnosis indicates a better outlook, with the risk of disease progression low, a study has found.

Faecal calprotectin levels shed light on Crohn’s disease course

01 Sep 2020

Psychosocial care in kids, teens with IBD needs improving

30 Aug 2020

There continue to be gaps in the psychosocial care of children with inflammatory bowel diseases (IBDs), necessitating better and more comprehensive models of delivery, a recent study has found.

Psychosocial care in kids, teens with IBD needs improving

30 Aug 2020

Serrated polyps up long-term risk of colorectal cancer

29 Aug 2020

Having proximal serrated polyps, particularly large ones, is a risk factor for the long-term development of colorectal cancer, a recent study has found.

Serrated polyps up long-term risk of colorectal cancer

29 Aug 2020

Eosinophilic esophagitis remission maintained on orodispersible budesonide

29 Aug 2020 by

Eosinophilic esophagitis patients may successfully maintain their remission up to 48 weeks on a budesonide orodispersible tablet, without any serious treatment-related adverse events, according to the results of a phase III trial.

Eosinophilic esophagitis remission maintained on orodispersible budesonide

29 Aug 2020

Hydrogel spacer may reduce prostate radiotherapy-induced rectal complications

28 Aug 2020 by

The placement of an absorbable perirectal hydrogel spacer (HS) led to prostate-rectum separation with less rectal irradiation, fewer rectal toxicities, and better bowel-related quality of life (QoL) in men undergoing radiotherapy (RT) for prostate cancer (PCa), a meta-analysis has shown.

Hydrogel spacer may reduce prostate radiotherapy-induced rectal complications

28 Aug 2020

From 20 to 5 min: Shortened read time of rapid HCV antibody test just as sensitive

26 Aug 2020 by

Reducing the wait time for the hepatitis C virus (HCV) rapid antibody point-of-care test, from 20 minutes to 5 minutes, does not affect its sensitivity and is just as good for ruling out infection, according to a study.

From 20 to 5 min: Shortened read time of rapid HCV antibody test just as sensitive

26 Aug 2020

Biologic–immunomodulator combo of no benefit in inflammatory bowel disease

25 Aug 2020 by

In the treatment of patients with Crohn’s disease or ulcerative colitis, adding an immunomodulator to ustekinumab or vedolizumab has a null effect on key outcomes, including clinical remission or response, endoscopic remission, and persistence of therapy at 1 year, as shown in a study.

Biologic–immunomodulator combo of no benefit in inflammatory bowel disease

25 Aug 2020

TNF antagonists safe for IBD patients with COVID-19

25 Aug 2020 by

The use of tumour necrosis factor (TNF) antagonists does not lead to a worse prognosis in patients with coronavirus disease 2019 (COVID-19), according to a new study. Systemic corticosteroids, on the other hand, appear to be a significant risk factor for severe disease.

TNF antagonists safe for IBD patients with COVID-19

25 Aug 2020

Treatment scale-up among injectable drug users key to HCV elimination in SG

24 Aug 2020 by

Achieving the World Health Organization’s (WHO) target to eliminate hepatitis C virus (HCV) by 2030 is possible in Singapore, but this requires immediate scaling up of treatment among injectable drug users (IDUs) together with harm reduction efforts, as suggested in a study.

Treatment scale-up among injectable drug users key to HCV elimination in SG

24 Aug 2020

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CEA may predict better survival with targeted therapy in mCRC

CEA may predict better survival with targeted therapy in mCRC

Faecal calprotectin levels shed light on Crohn’s disease course

Faecal calprotectin levels shed light on Crohn’s disease course

Psychosocial care in kids, teens with IBD needs improving

Psychosocial care in kids, teens with IBD needs improving

Serrated polyps up long-term risk of colorectal cancer

Serrated polyps up long-term risk of colorectal cancer

Eosinophilic esophagitis remission maintained on orodispersible budesonide

Eosinophilic esophagitis remission maintained on orodispersible budesonide

Hydrogel spacer may reduce prostate radiotherapy-induced rectal complications

Hydrogel spacer may reduce prostate radiotherapy-induced rectal complications

From 20 to 5 min: Shortened read time of rapid HCV antibody test just as sensitive

From 20 to 5 min: Shortened read time of rapid HCV antibody test just as sensitive

Biologic–immunomodulator combo of no benefit in inflammatory bowel disease

Biologic–immunomodulator combo of no benefit in inflammatory bowel disease

TNF antagonists safe for IBD patients with COVID-19

TNF antagonists safe for IBD patients with COVID-19

Treatment scale-up among injectable drug users key to HCV elimination in SG

Treatment scale-up among injectable drug users key to HCV elimination in SG