News &amp; Updates

The allosteric inhibitor asciminib shows clinical activity in heavily pretreated patients with chronic myeloid leukaemia who have failed or cannot tolerate tyrosine kinase inhibitors, including those who do not respond to ponatinib and harbour a T315I mutation, according to the results of a phase I dose-escalation study.

Asciminib shows therapeutic potential in chronic myeloid leukaemia

Repaglinide, acarbose effective for postprandial glycaemic control in type 2 diabetes

Both acarbose and repaglinide are effective for the control of postprandial hyperglycaemia in type 2 diabetes patients, a new study has found.

Repaglinide, acarbose effective for postprandial glycaemic control in type 2 diabetes

Every-2-month cabotegravir + rilpivirine feasible for HIV treatment

Every-two-month injections of the long-acting cabotegravir + rilpivirine were noninferior to once-monthly injections for virologic suppression at 48 weeks in people living with HIV*, according to the ATLAS-2M** study presented at CROI 2020 — thus providing a potential option with more convenient dosing.

Every-2-month cabotegravir + rilpivirine feasible for HIV treatment

Hydrochlorothiazide diuretic helps with fluid drainage during breast reconstruction

Hydrochlorothiazide helps lessen the accumulation of interstitial fluid during deep inferior epigastric perforator (DIEP) flap breast reconstruction, a recent study has shown.

Hydrochlorothiazide diuretic helps with fluid drainage during breast reconstruction

Upping step count could reduce T2D, hypertension risk

A study presented at the recent EPI Scientific Sessions showed that increasing step count could reduce the risk of developing type 2 diabetes (T2D) and hypertension.

Upping step count could reduce T2D, hypertension risk

$Add-on IW-3718 relieves heartburn symptoms in refractory GERD$

Add-on IW-3718 relieves heartburn symptoms in refractory GERD

Use of the bile acid sequestrant IW-3718 as an adjunct to proton pump inhibitor (PPI) therapy is well tolerated and reduces heartburn and regurgitation symptoms in patients with refractory gastro-oesophageal reflux disease (GERD), according to the results of a trial.

Add-on IW-3718 relieves heartburn symptoms in refractory GERD

Dual trumps triple therapy in reducing bleeding risk in AF patients after PCI

Treatment with direct oral anticoagulant (DOAC) plus P2Y12 inhibitor (dual therapy) in adults with nonvalvular atrial fibrillation (AF) after percutaneous coronary intervention (PCI) reduces bleeding risk compared with vitamin K antagonist plus aspirin and P2Y12 inhibitor (triple therapy), suggest a study.

Dual trumps triple therapy in reducing bleeding risk in AF patients after PCI

Habitual yogurt consumption may prevent NAFLD development

A recent study involving Chinese adults has shown that higher consumption of yogurt can potentially reduce the prevalence of newly diagnosed nonalcoholic fatty liver disease (NAFLD).

Habitual yogurt consumption may prevent NAFLD development

Cannabinoids, SSRIs ineffective against cannabis use disorder

Several pharmacologic interventions, including cannabinoids and selective serotonin reuptake inhibitors (SSRIs), do not appear to be effective in the treatment of cannabis use disorder (CUD), a study has shown.

Cannabinoids, SSRIs ineffective against cannabis use disorder

COVID-19 frontliners face depression, distress

Physicians and nurses in hospitals equipped with fever clinics or wards for patients with coronavirus disease 2019 (COVID-19) in China report experiencing symptoms of depression, anxiety, insomnia and distress, according to a recent survey.

COVID-19 frontliners face depression, distress