News & Updates

CARMELINA: Linagliptin lowers albuminuria in T2D patients with nephrotic-range proteinuria

26 Jan 2021 by

In patients with type 2 diabetes (T2D) and nephrotic-range proteinuria, treatment with the dipeptidyl peptidase-4 (DPP-4) inhibitor linagliptin helps reduce albuminuria burden and manage blood sugar at the same time, without increasing the risk of adverse cardiovascular or kidney events, according to data from the CARMELINA trial.

CARMELINA: Linagliptin lowers albuminuria in T2D patients with nephrotic-range proteinuria

26 Jan 2021

BMI cutoff for overweight needs readjustment in Asians, says study

26 Jan 2021 by

Body mass index (BMI) levels both above and below 25.0–29.9 kg/m2 are associated with increased mortality in a population without pre-existing disease, suggesting that the current cutoff of overweight (BMI ≥23 kg/m2) may need re-evaluation and that BMI alone may not be an accurate measure for indicating adiposity in Asians, according to a prospective cohort study in Korea.

BMI cutoff for overweight needs readjustment in Asians, says study

26 Jan 2021

Adding chemo to endocrine therapy may benefit premenopausal women with early breast cancer

25 Jan 2021 by

The addition of chemotherapy to endocrine therapy improved invasive disease-free survival (IDFS) in premenopausal women with lymph node-positive early stage hormone receptor-positive (HR+) HER2-negative (HER2-) breast cancer with recurrence score ≤25, according to early results of the phase III SWOG S1007 RxPonder* trial presented at SABCS 2020. However, the benefits did not appear to extend to postmenopausal women.

Adding chemo to endocrine therapy may benefit premenopausal women with early breast cancer

25 Jan 2021

Sotagliflozin SCORED favourably in patients with T2D, CKD

25 Jan 2021 by

Use of the sodium-glucose cotransporter 2 (SGLT2) inhibitor sotagliflozin led to a reduction in the risk of deaths from cardiovascular (CV) causes, hospitalizations for heart failure (HF), and urgent visits for HF compared with placebo among patients with type 2 diabetes (T2D) and chronic kidney disease (CKD) regardless of the degree of albuminuria, the SCORED* trial has shown.

Sotagliflozin SCORED favourably in patients with T2D, CKD

25 Jan 2021

Higher fasting glucose level tied to increase risk of diabetes in PCOS

25 Jan 2021

Among women with polycystic ovary syndrome (PCOS), higher baseline fasting glucose levels are linked to an increased incidence of type 2 diabetes mellitus, a study reports.

Higher fasting glucose level tied to increase risk of diabetes in PCOS

25 Jan 2021

Prediabetes negatively affects physical function

24 Jan 2021

Prediabetes contributes to faster functional decline and disability, irrespective of the future development of diabetes, a study suggests. This association is partly mediated by cardiovascular diseases.

Prediabetes negatively affects physical function

24 Jan 2021

Plasma creatine may foretell diabetes in men

23 Jan 2021

Plasma creatine concentrations are lower in men than in women, and men with higher plasma creatine are at greatly increased risk of developing type 2 diabetes, according to data from the PREVEND study.

Plasma creatine may foretell diabetes in men

23 Jan 2021

Vitamin D status in infancy inversely tied to cardiometabolic health in adolescence

23 Jan 2021

Serum 25-hydroxyvitamin D (25[OH]D) at age 1 year shows an inverse association with childhood body mass index for age z score (BMIZ), percentage body fat at age 16/17 years, and a metabolic syndrome (MetS) score at age 16/17 years, a recent study has found.

Vitamin D status in infancy inversely tied to cardiometabolic health in adolescence

23 Jan 2021

Taking more dietary fibre may improve bone health

23 Jan 2021

Higher intake of total dietary fibre and subtypes from various food sources appears to enhance heel bone mineral density (BMD), according to a study. Individuals with lower genetically determined propionate production may benefit from consuming more dietary fibre.

Taking more dietary fibre may improve bone health

23 Jan 2021

CTRP9 a potential biomarker for cardiac autonomic neuropathy in T2DM

23 Jan 2021

Levels of the C1q tumour necrosis factor-related protein 9 (CTRP9) adipokine correlate significantly and independently with cardiac autonomic neuropathy (CAN) in diabetics, a new study has shown.

CTRP9 a potential biomarker for cardiac autonomic neuropathy in T2DM

23 Jan 2021

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CARMELINA: Linagliptin lowers albuminuria in T2D patients with nephrotic-range proteinuria

CARMELINA: Linagliptin lowers albuminuria in T2D patients with nephrotic-range proteinuria

BMI cutoff for overweight needs readjustment in Asians, says study

BMI cutoff for overweight needs readjustment in Asians, says study

Adding chemo to endocrine therapy may benefit premenopausal women with early breast cancer

Adding chemo to endocrine therapy may benefit premenopausal women with early breast cancer

Sotagliflozin SCORED favourably in patients with T2D, CKD

Sotagliflozin SCORED favourably in patients with T2D, CKD

Higher fasting glucose level tied to increase risk of diabetes in PCOS

Higher fasting glucose level tied to increase risk of diabetes in PCOS

Prediabetes negatively affects physical function

Prediabetes negatively affects physical function

Plasma creatine may foretell diabetes in men

Plasma creatine may foretell diabetes in men

Vitamin D status in infancy inversely tied to cardiometabolic health in adolescence

Vitamin D status in infancy inversely tied to cardiometabolic health in adolescence

Taking more dietary fibre may improve bone health

Taking more dietary fibre may improve bone health

CTRP9 a potential biomarker for cardiac autonomic neuropathy in T2DM

CTRP9 a potential biomarker for cardiac autonomic neuropathy in T2DM