News &amp; Updates

A once-weekly prophylactic dose of azithromycin does not improve lung function in children with HIV-associated chronic lung disease (HCLD), according to results of the BREATHE* trial. However, azithromycin was associated with a reduction in acute respiratory exacerbations (AREs).

Prophylactic azithromycin does not improve lung function in paediatric HIV-related lung disease

Omadacycline noninferior to moxifloxacin in patients with PORT risk class III, IV CABP

In the treatment of patients with community-acquired bacterial pneumonia (CABP), omadacycline is as effective as moxifloxacin at inducing response in patients with Pneumonia Patient Outcomes Research Team (PORT) risk class III and IV, according to data from the phase III OPTIC* trial.

Omadacycline noninferior to moxifloxacin in patients with PORT risk class III, IV CABP

Gut dysbiosis linked to COVID-19 severity and persistent symptoms after viral clearance

Altered gut microbiota composition in patients with coronavirus disease 2019 (COVID-19) compared with controls is linked to COVID-19 severity and may contribute to persistent symptoms after viral clearance, according to a study by the Chinese University of Hong Kong (CUHK).

Gut dysbiosis linked to COVID-19 severity and persistent symptoms after viral clearance

Severe COVID-19 triggers robust T cell memory

Recent research has shown that the population of CD8+ T cells targeting SARS-CoV-2 are very diverse. Patients who recover from a severe episode of the novel coronavirus disease (COVID-19) tend to have robust T cell memory responses, as opposed to a more exhausted, restrained repertoire of cells found in those who only developed mild disease.

Severe COVID-19 triggers robust T cell memory

Baricitinib-remdesivir combo may improve COVID-19 recovery time

The combination of baricitinib and remdesivir improved recovery time and clinical status of patients with COVID-19 compared with remdesivir monotherapy, results of the ACTT*-2 study showed.

Baricitinib-remdesivir combo may improve COVID-19 recovery time

COVID-19 brain complications up with diabetes, hypertension

Patients with diabetes and hypertension are at an increased risk for neurologic complications from COVID-19, and this makes an already bad prognosis into worse, reports an expert at RSNA 2020.

COVID-19 brain complications up with diabetes, hypertension

B-cells remember COVID-19, protect against reinfection

While antibody titres against SARS-CoV-2 wane with time, the immune system is capable of producing memory B-cells that can last for at least 6 months after infection, suggesting that the body will be able to protect itself in the case of re-exposure, according to a new study.

B-cells remember COVID-19, protect against reinfection

High morbidity and mortality among COVID-19 patients with haematologic malignancies

Patients with coronavirus disease 2019 (COVID-19) who have haematologic malignancies have a 28 percent mortality rate, according to data collected from 250 patients by the ASH Research Collaborative COVID-19 presented at the 62^nd American Society of Hematology Annual Meeting and Exposition (ASH 2020).

High morbidity and mortality among COVID-19 patients with haematologic malignancies