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Impaired RV function, pulmonary coupling tied to hospitalizations, death in HFpEF patients
Worsening right ventricular (RV) function normally occurs in patients with heart failure and preserved left ventricular ejection fraction (HFpEF) and, along with its ratio to pulmonary pressure, is predictive of a higher risk of HF hospitalizations and cardiovascular death, reports a study.
Impaired RV function, pulmonary coupling tied to hospitalizations, death in HFpEF patients
09 Aug 2023
Change in gait speed predicts hospitalization, death in IPF patients
A considerable decline of >0.07 m/s in 4-metre gait speed (4MGS) over 6 months is associated with a higher risk of all-cause, nonelective hospitalization or death over the next 6 months in patients with a newly diagnosed idiopathic pulmonary fibrosis (IPF), suggests a study.
Change in gait speed predicts hospitalization, death in IPF patients
09 Aug 2023
Second-line avelumab works against dMMR/MSI metastatic colorectal cancer
Treatment with the immune checkpoint inhibitor avelumab in the second-line setting confers survival and disease control benefits in patients with deficient mismatch repair and/or microsatellite instability (dMMR/MSI) metastatic colorectal cancer (mCRC) when compared with standard treatment, with a favourable safety profile, according to the results of the phase II SAMCO-PRODIGE 54 trial.
Second-line avelumab works against dMMR/MSI metastatic colorectal cancer
09 Aug 2023
Early gestational diabetes treatment modest at best in preventing adverse neonatal outcomes
Treatment of gestational diabetes before 20 weeks’ gestation appears to lead to a modestly lower incidence of a composite of adverse neonatal outcomes as compared with no-immediate treatment, with no substantial differences noted for pregnancy-related hypertension or neonatal lean body mass, as reported in a study.
Early gestational diabetes treatment modest at best in preventing adverse neonatal outcomes
09 Aug 2023
Experts call for early screening to lower colorectal cancer incidence
An expert-led public forum highlighted colorectal health awareness and early screening of people aged 45 and above, as key steps to reduce the burden of colorectal cancer (CRC) in Malaysia.
Experts call for early screening to lower colorectal cancer incidence
09 Aug 2023
Uncomplicated UTI: Choosing antibiotics based on resistance rates helps prevent treatment failure
In the treatment of individuals with uncomplicated urinary tract infection (UTI), the use of antibiotics with lower reported resistance rates such as amoxicillin-clavulanate and nitrofurantoin (AC + N) lowers the rate of treatment failure, as shown in a study from Singapore.
Uncomplicated UTI: Choosing antibiotics based on resistance rates helps prevent treatment failure
08 Aug 2023
GLP-1 RA, with or without SGLT2 inhibitors, prevents cardiac events in T2D
Treatment with the glucagon-like peptide-1 receptor agonist (GLP-1 RA) albiglutide results in fewer cardiovascular events, irrespective of sodium-glucose cotransporter-2 (SGLT2) inhibitor use, among patients with type 2 diabetes (T2D) and cardiovascular disease, according to the post hoc analysis of Harmony Outcomes*.
