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Biologic, thiopurine, methotrexate for IBD not detrimental to fertility
For male patients with inflammatory bowel disease (IBD), treatment with biologic, thiopurine, or methotrexate does not appear to promote impairments in fertility or adverse pregnancy outcomes, according to a study.
Biologic, thiopurine, methotrexate for IBD not detrimental to fertility
26 Jul 2022
Post-COVID-19 vax uveitis may be more common in Southeast Asia
COVID-19 vaccination-induced uveitis is uncommon, with cases mostly self-limiting and showing good responses to treatment with no long-term sequelae, according to a Singapore study. However, reactivation of such infections appears to occur at a higher proportion in Southeast Asia, where viral and toxoplasma infections are more common.
Post-COVID-19 vax uveitis may be more common in Southeast Asia
25 Jul 2022
Obese/overweight patients incur 10 percent long-term weight loss with lifestyle management, medication
Individuals who are overweight or obese can achieve an approximately 10 percent weight loss over 3–5 years with the use of anti-obesity medications in addition to lifestyle management, according to a retrospective study presented at ENDO 2022.
Obese/overweight patients incur 10 percent long-term weight loss with lifestyle management, medication
25 Jul 2022
Secondary analysis boosts potential of atogepant for migraine prophylaxis in adults
In the secondary analysis of the phase III ADVANCE trial, responder rates were markedly higher with atogepant irrespective of dose than with placebo in adults with migraine.
Secondary analysis boosts potential of atogepant for migraine prophylaxis in adults
25 Jul 2022
SG: COPD severity a key factor when choosing between therapies
Chronic obstructive pulmonary disease (COPD) patients initiating treatment with a long-acting muscarinic antagonist (LAMA) plus a long-acting β2-agonist (LABA) tend to have higher disease severity than those who are started on LAMA, according to real-world data from Singapore. However, there are as many patients who experience clinical worsening in the LAMA group as there are in the LAMA+LABA group.
SG: COPD severity a key factor when choosing between therapies
22 Jul 2022
HCV treatment helps prevent cirrhosis, death in persons who inject drugs
People who inject drugs (PWID) and are receiving treatment for hepatitis C virus (HCV) show a substantial decline in liver disease and mortality, according to a study.
HCV treatment helps prevent cirrhosis, death in persons who inject drugs
22 Jul 2022
Apremilast more efficacious in PsA patients with moderate vs high disease activity
Psoriatic arthritis (PsA) patients with moderate disease activity (MDA) at baseline who are treated with apremilast are more likely to achieve treatment targets than those with high disease activity (HDA), a recent study has shown.
Apremilast more efficacious in PsA patients with moderate vs high disease activity
22 Jul 2022
40 COVID-19 vaccines and counting: Do we still need more?
There are currently 40 approved vaccines against COVID-19, of which 11 have been granted Emergency Use Authorization by the World Health Organization. [covid19.trackvaccines.org/vaccines/approved] With over 300 other candidates in the development pipeline – over 100 of which are in clinical testing [vac-lshtm.shinyapps.io/ncov_vaccine_landscape] – are new vaccines necessary?