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UDCA-induced GLOBE score changes tied to survival in primary biliary cholangitis
In patients with primary biliary cholangitis (PBC), changes in the GLOBE score (ΔGLOBE) brought about by treatment with ursodeoxycholic acid (UDCA) are predictive of liver transplantation (LT)-free survival, reports a study.
UDCA-induced GLOBE score changes tied to survival in primary biliary cholangitis
04 Aug 2023
Head-to-head trial STAMPs asciminib mark in CML treatment landscape
In the exploratory analyses of the phase III ASCEMBL trial, individuals with chronic myeloid leukaemia in chronic phase (CML-CP) who have failed ≥2 prior tyrosine kinase inhibitors (TKIs) continued to achieve deep responses with asciminib, the first BCR::ABL1 inhibitor to Specifically Target the ABL Myristoyl Pocket (STAMP).
Head-to-head trial STAMPs asciminib mark in CML treatment landscape
04 Aug 2023
Saphnelo now available in Malaysia as an add-on treatment for adult patients with moderate to severe, active autoantibody-positive systemic lupus erythematosus (SLE)
AstraZeneca’s Saphnelo (anifrolumab) has now become available as add-on treatment for adult patients in Malaysia with moderate to severe, active autoantibody-positive systemic lupus erythematosus (SLE) following insufficient response to standard therapy, after obtaining regulatory approval earlier this year.
Saphnelo now available in Malaysia as an add-on treatment for adult patients with moderate to severe, active autoantibody-positive systemic lupus erythematosus (SLE)
04 Aug 2023
Memories of childhood maltreatment affect mental health more than the abuse itself
Young adults with memories of childhood maltreatment have a greater number of depressive or anxiety episodes in adulthood vs those with official court records but not memories of such maltreatment, a large longitudinal study has found.
Memories of childhood maltreatment affect mental health more than the abuse itself
04 Aug 2023
HDP exposure in gestation, maternal hypertension spell increased hypertension risk in offspring
Exposure to hypertensive disorders of pregnancy (HDP) in gestation and maternal hypertension both contribute to an elevated risk of chronic hypertension in offspring, as reported in a study.
HDP exposure in gestation, maternal hypertension spell increased hypertension risk in offspring
03 Aug 2023
Hybrid, bismuth quadruple therapies superior to high-dose dual therapy for H pylori eradication
In the first-line treatment of Helicobacter pylori (H pylori) infection, 14-day hybrid therapy and 10-day bismuth quadruple therapy demonstrate superiority over 14-day high-dose dual therapy, reports a Taiwan study. However, high-dose therapy results in fewer adverse events than hybrid bismuth quadruple therapies.